YRC Public Data Repository - Protein Structure Prediction

Protein:	dak1
Organism:	Schizosaccharomyces pombe
Length:	580 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dak1.

Description	E-value	Query Range	Subject Range
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1 DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1	670.0	[0..1]	[580..1]
DAK1_YEAST - Dihydroxyacetone kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAK1 PE=1 SV=1 DAK1 - Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a...	643.0	[0..1]	[579..1]
gi\|238032869, gi... - gi\|254571923\|ref\|XP_002493071.1\| Dihydroxyacetone kinase, required for detoxification of dihydroxyac... DAK_PICPA - Dihydroxyacetone kinase OS=Komagataella pastoris GN=DAK PE=3 SV=1 jgi\|Picpa1\|39132... - null	640.0	[0..1]	[578..1]
gi\|110674290, gi... - gi\|110799643\|ref\|YP_694559.1\| dihydroxyacetone kinase family protein [Clostridium perfringens ATCC 1...	636.0	[0..2]	[578..1]
gi\|18309082, gi\|... - gi\|18309082\|ref\|NP_561016.1\| dihydroxyacetone kinase [Clostridium perfringens str. 13], gi\|18143757\|...	634.0	[0..2]	[578..1]
gi\|44983723 - gi\|44983723\|gb\|AAS52822.1\| AER139Cp [Ashbya gossypii ATCC 10895] gi\|44983723, gi\|... - gi\|45190744\|ref\|NP_984998.1\| AER139Cp [Ashbya gossypii ATCC 10895], gi\|44983723\|gb\|AAS52822.1\| AER13...	629.0	[0..16]	[579..16]
orf19.4777 - DAK2 CGDID:CAL0004557 Assembly 19, Contig19-10215 (133747, 131960) CDS, reverse complemented, transl... gi\|46445497, gi\|... - gi\|68464771\|ref\|XP_723463.1\| hypothetical protein CaO19.4777 [Candida albicans SC5314], gi\|46445497\|... gi\|238878667 - gi\|238878667\|gb\|EEQ42305.1\| dihydroxyacetone kinase [Candida albicans WO-1]	622.0	[0..10]	[580..13]
gi\|42550160, gi\|... - gi\|46127329\|ref\|XP_388218.1\| hypothetical protein FG08042.1 [Gibberella zeae PH-1], gi\|42550160\|gb\|E...	616.0	[0..1]	[580..1]
gi\|11281433, gi\|... - gi\|3493578\|gb\|AAC78808.1\| dihydroxyacetone kinase [Schizosaccharomyces pombe], gi\|11281433\|pir\|\|T437...	614.0	[0..1]	[580..1]

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Predicted Domain #1

Region A:
Residues: [1-580]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKHFINDPE VLVLDGLKSL ADMNKTLTVH EEGKFIYFHD YNKKNVSVIS GGGAGHEPTH  60
   61 SSFVGKGMLT AAVSGSIFAS PSSKQIYTGI KQVESEAGTL VICKNYTGDI LHFGMALEKQ 120
  121 RTAGKKAELI AVADDVSVGR KKSGKVGRRG LSGTVLVHKI AGAAAARGLP LEAVTTIAKA 180
  181 AIDNLVSIGA SLAHVHVPGH EPIAKEDEMK HDEMELGMGI HNEPGCKRIS PIPSIDDLIA 240
  241 QMLKQMLDQS DKDRAYVKIE GDDEVVLLMN NLGGLSMLEF SAISHKVKEA LAKEYKINPV 300
  301 RIFAGPFTTS LNGLGFGITL LRTTDRVKVE GEEYSLVDLI DQPVEAIGWP LCQPSDLKSK 360
  361 NKIGNVSIEE GQKDVKSPVT VDKEKVRQAI VNSMENLIKA EPKITKFDTM AGDGDCGTTL 420
  421 KRGAEGVLKF VKSDKFSDDP IRIVRDIADV IEDNMDGTSG ALYAIFFHGF AKGMKDTLEK 480
  481 SKDISSKTWA AGLKVALDTL FKYTPARPGD STMCDALVPF VETFVKTNDL NAAVEEARKG 540
  541 ADATADMQAK LGRAVYVGDD VKVPDAGALG VVAIVEGFTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.0
Match:	1un8A
Description:	Crystal structure of the dihydroxyacetone kinase of C. freundii (native form)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycerone kinase activity	3.66907507772019	bayes_pls_golite062009
binding	0.69038000262198	bayes_pls_golite062009
catalytic activity	0.142389024724964	bayes_pls_golite062009
protein binding	0.133716715271428	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: