YRC Public Data Repository - Protein Structure Prediction

Protein:	cox5
Organism:	Schizosaccharomyces pombe
Length:	174 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cox5.

Description	E-value	Query Range	Subject Range
gi\|39942216, gi\|... - gi\|39942216\|ref\|XP_360645.1\| hypothetical protein MGG_03188 [Magnaporthe grisea 70-15], gb\|EAA51593....	204.0	[0..3]	[171..1]
COX5_NEUCR - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Neurospora crassa GN=cya-4 PE=3 SV=2 COX5_NEUCR - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-...	203.0	[0..3]	[167..1]
COX5_ASPNG - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Aspergillus niger GN=cox5 PE=3 SV=1	201.0	[0..7]	[171..34]
gi\|67523721, gi\|... - gi\|67523721\|ref\|XP_659920.1\| COX5_ASPNG Cytochrome c oxidase polypeptide V, mitochondrial precursor ...	200.0	[0..8]	[171..35]
gi\|7161891 - gi\|7161891\|emb\|CAB76570.1\| cytochrome c oxidase subunit V [Podospora anserina]	196.0	[0..7]	[165..6]
gi\|70997703, gi\|... - gi\|70997703\|ref\|XP_753588.1\| cytochrome c oxidase subunit V [Aspergillus fumigatus Af293], gi\|668512...	192.0	[0..7]	[171..34]
gi\|83776213 - gi\|83776213\|dbj\|BAE66332.1\| unnamed protein product [Aspergillus oryzae] gi\|169786009 - gi\|169786009\|ref\|XP_001827465.1\| hypothetical protein [Aspergillus oryzae RIB40]	191.0	[0..7]	[171..34]
gi\|88176393, gi\|... - gi\|88176393\|gb\|EAQ83861.1\| cytochrome c oxidase polypeptide V, mitochondrial precursor [Chaetomium g...	188.0	[0..3]	[165..4]
gi\|46116946, gi\|... - gi\|46116946\|ref\|XP_384491.1\| hypothetical protein FG04315.1 [Gibberella zeae PH-1], gi\|42550798\|gb\|E...	186.0	[0..3]	[164..1]
gi\|68137991 - gi\|68137991\|gb\|AAY85812.1\| mitochondrial cytochrome c oxidase subunit V [Chaetomium globosum]	184.0	[0..3]	[165..4]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLCTRNAA TVSAAATNAL QKEQPSGEAM IARPRLVDLD KRWGIMSQEE KDGLITDLYA  60
   61 RQKQPWTTLS IEEKKAAYWI AFGEHGPRAF SHISQKTVFW GTVAGLTIGV VLFGLIRTQA 120
  121 APSPRTMTRE WQEKSNEYMK ENKINPISGE ASEGFKGRGQ ISGGIFSPSE KDKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.39794
Match:	1occD
Description:	Mitochondrial cytochrome c oxidase subunit IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytochrome-c oxidase activity	12.8672436325695	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	12.8672436325695	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	12.8672436325695	bayes_pls_golite062009
heme-copper terminal oxidase activity	12.5536631591417	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	6.39367011108548	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	6.23942388461757	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.62960572959435	bayes_pls_golite062009
oxidoreductase activity	5.40847023303734	bayes_pls_golite062009
cation transmembrane transporter activity	5.36812403817205	bayes_pls_golite062009
ion transmembrane transporter activity	5.16334360779969	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.74071132470389	bayes_pls_golite062009
substrate-specific transporter activity	4.53098112436118	bayes_pls_golite062009
binding	1.31836143571093	bayes_pls_golite062009
protein binding	0.603394316928236	bayes_pls_golite062009
catalytic activity	0.600497727931764	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: