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View Structure Prediction Details

Protein: cdc10
Organism: Schizosaccharomyces pombe
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc10.

Description E-value Query
Range
Subject
Range
gi|108868779, gi... - gi|157106769|ref|XP_001649474.1| ankyrin 2,3/unc44 [Aedes aegypti], gi|108868779|gb|EAT33004.1| anky...
354.0 [0..49] [696..5]
gi|115877255, gi... - gi|115970262|ref|XP_001190373.1| PREDICTED: similar to ankyrin 2,3/unc44, partial [Strongylocentrotu...
325.0 [0..49] [695..37]
gi|66847484, gi|... - gi|70990006|ref|XP_749852.1| Pfs, NACHT and Ankyrin domain protein [Aspergillus fumigatus Af293], gi...
320.0 [0..23] [664..853]
gi|119525310, gi... - gi|119720190|ref|YP_920685.1| ankyrin [Thermofilum pendens Hrk 5], gi|119525310|gb|ABL78682.1| Ankyr...
319.0 [0..63] [674..188]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASANFIRQF ELGNDSFSYQ KRPEDEPSQP LSNRNINKLN DSSTLKDSSS RIFINSQVLR  60
   61 DGRPVELYAV ECSGMKYMEL SCGDNVALRR CPDSYFNISQ ILRLAGTSSS ENAKELDDII 120
  121 ESGDYENVDS K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1l3gA
Description: DNA-binding domain of Mlu1-box binding protein MBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [132-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPQIDGVWVP YDRAISIAKR YGVYEILQPL ISFNLDLFPK FSKQQQIESS SISKNLNTSS  60
   61 FNTRSPLRNH NFSNPSKSSK NGVHTINNMQ SSPSPSSSFL LPLTQIDSQN VKRSNNYLST 120
  121 SPPILEQRLK RHRIDVSDED LHPSSQLNDN EASSLFPDTP RLNHSLSFVS LVSSLPPLDQ 180
  181 NIMQDYHTSK DILTSIFLDV NFADSSALEA KLSDSLDLDV PIDELGHAAL HWAAAVAKMP 240
  241 LLQALIHKGA NPLRGNLTGE TALMRSVLVT NHLNQNSFGD LLDLLYASLP CTDRAGRTVV 300
  301 HHICLTAGIK GRGSASRYYL ETLLNWAKKH ASGNNGYMLK DFINYLNHQD KNGDTALNIA 360
  361 ARIGNKNIVE VLMQAGASAY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.045757
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
transcription activator activity 1.6418915400902 bayes_pls_golite062009
transcription repressor activity 1.57265102061447 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
sequence-specific DNA binding 0.949906091645366 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 0.68541709976608 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.590503097160372 bayes_pls_golite062009
protein kinase regulator activity 0.576422771673579 bayes_pls_golite062009
cytoskeletal protein binding 0.56201598804914 bayes_pls_golite062009
kinase regulator activity 0.4228431685549 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [512-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPNRAGLSVA NFGIFVENAL KQPEDSKQTK VSLMSENLSS KEKTAVPPRQ KSRDIIASVT  60
   61 DVISSLDKDF QDEMAAKQSM IDSAYTQLRE STKKLSDLRE QLHVSETQRT LFLELRQRCK 120
  121 NLMTSIEEQK SELSNLYESF DPNGIHDSLS LDADAPFTVN ENNNKNLSIA ELKFQVAAYE 180
  181 RNEARLNELA NKLWQRNSNI KSKCRRVVSL CTGVDESRVD SLLESLLQAV ESDGQQGEVD 240
  241 MGRVAGFLRV VKEHQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle