YRC Public Data Repository - Protein Structure Prediction

Protein:	arc4
Organism:	Schizosaccharomyces pombe
Length:	168 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arc4.

Description	E-value	Query Range	Subject Range
gi\|109474043, gi... - gi\|109474043\|ref\|XP_001078712.1\| PREDICTED: similar to actin related protein 2/3 complex, subunit 4 ...	332.0	[0..1]	[168..88]
gi\|50603869, gi\|... - gi\|57524652\|ref\|NP_001003762.1\| actin related protein 2/3 complex, subunit 4, like [Danio rerio], gi...	304.0	[0..1]	[168..1]
gi\|89267932, gi\|... - gi\|89267932\|emb\|CAJ83261.1\| actin related protein 2/3 complex, subunit 4 [Xenopus tropicalis], gi\|52... gi\|52078353, gi\|... - gi\|52078353\|gb\|AAH82370.1\| LOC494639 protein [Xenopus laevis], gi\|148236486\|ref\|NP_001087956.1\| hypo...	304.0	[0..1]	[168..1]
ARPC4 - actin related protein 2/3 complex, subunit 4, 20kDa gi\|195562233 - gi\|195562233\|gb\|ACG50184.1\| actin related protein 2/3 complex subunit 4 [Sus scrofa] gi\|57100910 - gi\|57100910\|ref\|XP_533747.1\| PREDICTED: similar to actin related protein 2/3 complex, subunit 4 [Can... gi\|157169642 - gi\|157169642\|gb\|AAI52791.1\| Actin related protein 2/3 complex, subunit 4, 20kDa [synthetic construct... ENSCJAT00000031460 - null ARPC4_MOUSE - Actin-related protein 2/3 complex subunit 4 OS=Mus musculus GN=Arpc4 PE=1 SV=3 tr\|G3GX96\|G3GX96... - Actin-related protein 2/3 complex subunit 4 OS=Cricetulus griseus GN=I79_002331 PE=3 SV=1 tr\|F6PH57\|F6PH57... - Actin-related protein 2/3 complex subunit 4 OS=Equus caballus OX=9796 GN=ARPC4 PE=3 SV=1 ARPC4_BOVIN - Actin-related protein 2/3 complex subunit 4 OS=Bos taurus GN=ARPC4 PE=1 SV=3 gi\|187469309, gi... - gi\|34858314\|ref\|XP_238365.2\| PREDICTED: similar to actin related protein 2/3 complex, subunit 4 [Rat... gi\|160904173 - gi\|160904173\|gb\|ABX52159.1\| actin related protein 2/3 complex, subunit 4, 20kDa, isoform 3 (predicte...	303.0	[0..1]	[168..1]
gi\|61367681, gi\|... - gi\|61367681\|gb\|AAX43031.1\| actin related protein 2/3 complex subunit 4 [synthetic construct], gi\|613...	303.0	[0..1]	[168..1]
gi\|12857620 - gi\|12857620\|dbj\|BAB31059.1\| unnamed protein product [Mus musculus]	302.0	[0..1]	[168..1]
AGAP001306-PA - actin related protein 2/3 complex, subunit 4\|protein_coding\|2R:2802451:2802957:1\|gene:AGAP001306 gi\|58396352, gi\|... - gi\|58396352\|ref\|XP_321841.2\| AGAP001306-PA [Anopheles gambiae str. PEST], gi\|55234038\|gb\|EAA01786.3\|...	302.0	[0..1]	[168..1]
gi\|47229588 - gi\|47229588\|emb\|CAG06784.1\| unnamed protein product [Tetraodon nigroviridis]	301.0	[0..2]	[168..2]

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Predicted Domain #1

Region A:
Residues: [1-168]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTLRPYLN AVRSTLTASL ALEEFSSEIV ERQSQPEVEV GRSPEILLKP LVVSRNEQEQ  60
   61 CLIESSVNSV RFSIRIKQVD EIERILVRKF MQFLMGRAES FFILRRKPVQ GYDISFLITN 120
  121 YHTEEMLKHK LVDFIIEFME EVDAEISEMK LFLNGRARLV AETYLSCF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.0
Match:	1k8kF
Description:	ARPC4 (20 kDa subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	6.0922573068519	bayes_pls_golite062009
actin filament binding	5.01990273175321	bayes_pls_golite062009
cytoskeletal protein binding	4.64781612293343	bayes_pls_golite062009
binding	2.16088008530271	bayes_pls_golite062009
structural constituent of cytoskeleton	1.37010524302636	bayes_pls_golite062009
protein binding	0.932082028882932	bayes_pls_golite062009
structural molecule activity	0.83499804393822	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: