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View Structure Prediction Details

Protein: FBpp0312074, mst-PA
Organism: Drosophila melanogaster
Length: 574 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0312074, mst-PA.

Description E-value Query
Range
Subject
Range
gi|47229230 - gi|47229230|emb|CAG03982.1| unnamed protein product [Tetraodon nigroviridis]
501.0 [0..1] [571..549]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYTREILTF QFGTYANYVG THFWNQQEAN FRYGDESEQV AEEQLPNNDI LYREGRNDLN  60
   61 RTTYTPRLLS VDLSGTLGHL PVTGELYGNF VQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.64
Match: 1ffxB
Description: Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [93-574]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDEELLPLST GEELEQVRKR AEESGVCSPE QLEVQEQSKA SISEYQRDLL KNAVVPEKNY  60
   61 QLAATANSWV DFLYARYHPR TLNVLPGLIR DPTAQALGTY SAGTEMWQEV SFNEEFCDRI 120
  121 RLYVEECDGL QGFHVLFDID DGFGGLAGKC LEHLNDEYSR ASFALPLHYP RITSYPQADT 180
  181 RLSHSIRVVN NVLGYHQLSE QALMFTPLST LETIWRNNNL KSRSLPGLQW ETDNLYQTSA 240
  241 LLAAFFDTAT LSYRLRQTPE SLLRFCECVT PAGRKMTAAG LALPFGLREG QDLIEFLDQS 300
  301 GDHALLTQLT PGCEPGTSYV VQSVTARGIP AERLKRPREL AGDQLRMAAY SCDSISHMLQ 360
  361 LYYQCTYHGS VTNAAATPLP LKTQLPFPYE MFAAGISRDG YRLPEGAERE TGSRVDSAPM 420
  421 LAAVQNSTKL GEHLDNVHAQ SHRVQLAKLQ AYSNSGLERD EYDTALDQLL EFRDLYADSQ 480
  481 YL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.0
Match: 1z2bA
Description: Tubulin-colchicine-vinblastine: stathmin-like domain complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of cytoskeleton 3.35383615286781 bayes_pls_golite062009
GTPase activity 1.47429346598123 bayes_pls_golite062009
binding 1.42787010326985 bayes_pls_golite062009
cytoskeletal protein binding 1.34163967063748 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.30976970862305 bayes_pls_golite062009
pyrophosphatase activity 1.23995409691722 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.2207183653046 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.21864338056199 bayes_pls_golite062009
protein binding 0.764892815699872 bayes_pls_golite062009
structural molecule activity 0.64964215487581 bayes_pls_golite062009
hydrolase activity 0.0508375661543299 bayes_pls_golite062009
tubulin binding 0.0306519764509874 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle