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View Structure Prediction Details

Protein: car-PA, car-PB
Organism: Drosophila melanogaster
Length: 617 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for car-PA, car-PB.

Description E-value Query
Range
Subject
Range
gi|114647527 - gi|114647527|ref|XP_001167604.1| PREDICTED: vacuolar protein sorting 33A isoform 4 [Pan troglodytes]
VPS33A - vacuolar protein sorting 33 homolog A (S. cerevisiae)
gi|109099110 - gi|109099110|ref|XP_001098683.1| PREDICTED: similar to vacuolar protein sorting 33A isoform 2 [Macac...
gi|157928837 - gi|157928837|gb|ABW03704.1| vacuolar protein sorting 33 homolog A (S. cerevisiae) [synthetic constru...
498.0 [0..1] [616..1]

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Predicted Domain #1
Region A:
Residues: [1-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPHLKGHGQ RVNLQLLQEA ACRELLQQLD RIEGSKVIVL DETMIGPLDL VTRPKLFADR  60
   61 GIRLLALKPE LHLPREVANV VYVMRPRVAL MEQLAAHVKA GGRAAAGRQY HILFAPRRSC 120
  121 LCVSQLEVSG VLGSFGNIEE LAWNYLPLDV DLVSMEMPNA FRDVSVDGDT SSLYQAAVGL 180
  181 VQLQRLYGRI PKIYGKGEFA HRVWEHAKQL GRDERTLYNG DKGVVDQLIL LDRSIDLLSP 240
  241 LATQLTYEGL IDEFYGIRQN KLTLPAENFP SDGALPGGGG SGPRVEESQS LLGDTEKKTI 300
  301 LLHSGEQLYA ELRNKHFNEV TKLLARKARE IHVQMHATSQ DKSVQEIKSF VENLLPQLMA 360
  361 QKKATSEHTA IAGLLHEQVN AVRFADDLAA EQEFMVCADI DKPSAYIEDL IACRVELNRV 420
  421 LRLICMQCHA ASGFKEKLLN HYKRELVHVY GLEVLLTISN LEKSGLLHLQ TESRAYSVLR 480
  481 KTLHLTVDDN VEIEPKDISY VHSFYAPLTA RIVEHSLKPL GWQTLKSQIN NLPGPTFEDF 540
  541 QAQLVGIGGR HTVTTVSEGS LLNVPRVVLV CFVGGCTFAE IAALRFLAAQ EDNNVEFLIA 600
  601 TTKVVNKHSF LDSLMSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 137.0
Match: 1dn1A
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNARE binding 3.42828022195984 bayes_pls_golite062009
binding 2.7837022903231 bayes_pls_golite062009
syntaxin binding 2.11416428645287 bayes_pls_golite062009
protein binding 1.7224010512877 bayes_pls_golite062009
syntaxin-1 binding 0.269372794919901 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle