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View Structure Prediction Details

Protein: Taf8-PA
Organism: Drosophila melanogaster
Length: 328 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Taf8-PA.

Description E-value Query
Range
Subject
Range
gi|17946385 - gi|17946385|gb|AAL49226.1| RE65343p [Drosophila melanogaster]
359.0 [0..1] [328..1]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKVEAVTVS NVDPYRRILN KVVSQLLLDK GAGQASNHSL ETLTQMLQAL IWEIGNSAHN  60
   61 YCELSGRTMP TVGDVSLALI NMGISISNLD PYMRKETHVP IPLPPQQTQQ RPLSLLQAGI 120
  121 KAPHPHYVPS YFPPMPDPHA YIRTPTHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1tafA
Description: TAF(II)42
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 9.25279783093877 bayes_pls_golite062009
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
transcription initiation factor activity 3.96621818094279 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.28941584139552 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
transcription activator activity 2.58408368884371 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
protein binding 2.1291876005999 bayes_pls_golite062009
sequence-specific DNA binding 1.18653213156155 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
nucleotidyltransferase activity 1.10331930589736 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription repressor activity 0.72554769377984 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0792897588268993 bayes_pls_golite062009
transcription corepressor activity 0.0736756545988504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [149-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPVTEYEAIR EKAACQKRDI EKALTKFLCK TTETNNLFPT EDNMFPLIAC KPAFPPYAAA  60
   61 LNPTDQVFDF EELEYHYLVA NRTEDEPSKD DGEEGDSENE EMDGDKSKEE KPELDIKPNS 120
  121 NTNKAILENP NIDNPYLRAA TLPKRSKNCP TPGTMPSRSL ATTAPTIRTP STLEITKTNL 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle