YRC Public Data Repository - Protein Structure Prediction

Protein:	CG5703-PA, FBpp0...
Organism:	Drosophila melanogaster
Length:	242 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5703-PA, FBpp0....

Description	E-value	Query Range	Subject Range
NDUV2_MOUSE - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Mus musculus GN=Ndufv2 PE=1 SV=2	356.0	[0..1]	[242..1]
gi\|109121568 - gi\|109121568\|ref\|XP_001099724.1\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein ...	356.0	[0..15]	[242..20]
gi\|73962198 - gi\|73962198\|ref\|XP_537328.2\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 2, 2...	355.0	[0..2]	[242..3]
NDUV2_RAT - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Rattus norvegicus GN=Ndufv2 PE=1 SV...	355.0	[0..1]	[242..1]
NDUV2_PONPY - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo pygmaeus GN=NDUFV2 PE=2 SV=1 gi\|111661782 - gi\|111661782\|gb\|ABH12155.1\| mitochondrial complex I subunit NDUFV2 [Gorilla gorilla] NDUV2_PONAB - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo abelii GN=NDUFV2 PE=2 SV=1 NDUV2_GORGO - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Gorilla gorilla gorilla GN=NDUFV2 P...	354.0	[0..15]	[242..20]
gi\|119622017, gi... - pir\|\|A30113 NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) 24K chain precursor - human, gi\|48735289\|...	354.0	[0..15]	[242..20]
NDUV2_PANTR - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pan troglodytes GN=NDUFV2 PE=2 SV=1	354.0	[0..15]	[242..20]
NDUV2_BOVIN - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Bos taurus GN=NDUFV2 PE=1 SV=3	353.0	[0..16]	[242..21]

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Predicted Domain #1

Region A:
Residues: [1-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTNCASKTL AAVRANIRAI ATSSARASDN LFVHRDTPED NPNIPFEFTA ENKKRVEAIL  60
   61 SIYPEGHKRG AMIPLLDLAQ RQYGWLPISA MHKVAEILQL PNMRVYEVAT FYTMFMRKPT 120
  121 GKYHIQVCTT TPCWLRGSDD ILETCKKQLG IGVGDTTKDR KFTISEVECL GACVNAPMVA 180
  181 INDDYYEDLT SKDMQDILND LKADKISPPG PRNGRFASEP KGEPTSLSEE PKGPGFGLQA 240
  241 GL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	2fug2
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	9.90105969982332	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	8.92078442660684	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	8.81403581008074	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	8.78237088091479	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	8.15019987387908	bayes_pls_golite062009
oxidoreductase activity	4.56566449113494	bayes_pls_golite062009
electron carrier activity	1.9747415675561	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.64327334394445	bayes_pls_golite062009
glutathione transferase activity	0.441941661513454	bayes_pls_golite062009
binding	0.39192669546254	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	0.36869630503451	bayes_pls_golite062009
protein binding	0.157273259994554	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: