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View Structure Prediction Details

Protein: B-H1-PA
Organism: Drosophila melanogaster
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for B-H1-PA.

Description E-value Query
Range
Subject
Range
gi|73999130 - gi|73999130|ref|XP_544097.2| PREDICTED: similar to chromodomain helicase DNA binding protein 7 isofo...
169.0 [0..5] [542..37]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDSMSILTQ TPSEPNAAHP QLHHHLSTLQ QQHHQHHLHY GLQPPAVAHS IHSTTTMSSG  60
   61 GSTTTASGIG KPNRSRFMIN DILAGSAAAA FYKQQQHHQQ LHHHNNNNNS GSSGGSSPAH 120
  121 SNNNNN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [127-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INGDNCEASN VAGVGVLPSA LHHPQPHPPT HPHTHPHALM HPHGKLGHFP PTAGGNGLNV  60
   61 AQYAAAMQQH YAAAAAAAAA RNNAAAAAAA AAAAAAAGVA APPVDGGVDG GVGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [241-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APPAGGDLDD SSDYHEENED CDSGNMDDHS VCSNGGKDDD GNSVKSGSTS DMSGLSKKQR  60
   61 KARTAFTDHQ LQTLEKSFER QKYLSVQERQ ELAHKLDLSD CQVKTWYQNR RTKWKRQTAV 120
  121 GLELL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.30103
Match: 1b72A
Description: Homeobox protein hox-b1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.6809639302471 bayes_pls_golite062009
DNA binding 2.45264254102339 bayes_pls_golite062009
nucleic acid binding 2.32767577674158 bayes_pls_golite062009
binding 2.12643314274039 bayes_pls_golite062009
transcription factor activity 1.9610710007594 bayes_pls_golite062009
sequence-specific DNA binding 0.71974400731667 bayes_pls_golite062009
protein binding 0.57484570028668 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.328460252819506 bayes_pls_golite062009
transcription repressor activity 0.245215140763955 bayes_pls_golite062009
transcription activator activity 0.0177888191364471 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [366-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEAGNFAAFQ RLYGGSPYLG AWPYAAAAGA AHGATPHTNI DIYYRQAAAA AAMQKPLPYN  60
   61 LYAGVPSVGV GVGVGVGPAP FSHLSASSSL SSLSSYYQSA AAAASAANPG GPHPVAPPPS 120
  121 VGGGSPPSGL VKPIPAHSAS ASPPPRPPST PSPTLNPGSP PGRSVDSCSQ SDDEDQIQV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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