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View Structure Prediction Details

Protein: FBpp0293026, FBp...
Organism: Drosophila melanogaster
Length: 1436 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293026, FBp....

Description E-value Query
Range
Subject
Range
FBpp0293023 - type=protein; loc=X:join(17153508..17154364,17156673..17157011,17162552..17163022,17163964..17164147...
1289.0 [0..69] [1436..555]

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Predicted Domain #1
Region A:
Residues: [1-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSHQLDSYL GGVGSMMNLG GMGQVGQMYH PGSVSGSERP NGGALALHYA AARGCLDCVQ  60
   61 LLVAASVDIC ANTQMDNDVT PVYLAAQEGH LEVLKFLVLE AGGSLYVRAR DGMAPIHAAS 120
  121 QMGCLDCLKW MVQDQGVDPN LRDGDGATPL HFAASRGHLS VVRWLLNHGA KLSLDKYGKS 180
  181 PINDAAENQQ VECLNVLVQH GTSVDYNGKS SSQRHKSQQQ LHQQHQQQQQ QQQQQHLSSS 240
  241 CNSNSNSSKQ TSRSNTIKSK SSSTLSSDVE PFYLHPPALA GGSGGSGMGL GMGMGMGMGM 300
  301 SMGLGISRKN SDALYSQQSR SSSEKLYNGS SSLGGNPGGN SSSGGGGVGG GGGSGGALLP 360
  361 NDGLYVNPMR NGGMYNTPSP NGSISGESFF LHDPQDIIYN RVRDLFVDSD CSSSVKQHGK 420
  421 SHAHQLLQSK AGNAMTIQAD VHSSSSGAGS GSDESVSISS SFNSPKQQQQ LRSQSFNRHG 480
  481 SSSNISASGN I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.69897
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.30812396303844 bayes_pls_golite062009
actin binding 3.15358758538214 bayes_pls_golite062009
structural constituent of cytoskeleton 2.4948065111495 bayes_pls_golite062009
binding 2.03195138036959 bayes_pls_golite062009
actin filament binding 1.8758804992293 bayes_pls_golite062009
protein binding 1.6716587413544 bayes_pls_golite062009
myosin binding 1.55894148251645 bayes_pls_golite062009
myosin phosphatase activity 0.991228379874891 bayes_pls_golite062009
structural constituent of muscle 0.304639267984357 bayes_pls_golite062009
structural molecule activity 0.242743465134414 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [492-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNNNYKAHKG KPSNQNGGGD HDYEDIYLVR EESRKQHQQQ QQHQLQQQQQ LQHQATQQQQ  60
   61 QQQQQQQQLQ HKYNVGRSRS RDSGSHSRSA SASSTRSTDI VLQYSNHHLN NKRNMNNNSN 120
  121 MNNSSSNIAQ SSSSNNNNNS LLNRNKSHSI IGLHSSKYES SLKDNYSAKN VNLKNQLLNG 180
  181 GIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [675-757]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDTYESVCPP EDVAERTKQT HKNSMIRNNL ADASSNNNTS GSINNISNIG NMNGGNQSSR  60
   61 NLKRVSSAPP MQNLAVVNGP PPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [758-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPPPLRAPV QQQRNNLSVD QPNSMTGNNG IYKKNVFGPN QGPTNANGTG GAAPPPVPAP  60
   61 NPVATE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [824-1023]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVDSDSGLEV VEEPSLRPSE LVRGNHNRTM STISANKKAK LLNAGSTNGS SIAASSDDSQ  60
   61 SRYGGSVHAA NGSAANGHFY GYSEGNKNQG SNGNGNGNGN GGGGNYHSHP NQPHYATGQP 120
  121 HQYTPSLYGG GSSAEDHYEL TQQQQQIYGE THLPSGQRTG GPNLVNKQLV LPFVPPSFPN 180
  181 KSQDGVTHLI KPSEYLKSIS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1024-1129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDKRSCPSSA RSTDTEDYMQ IQIAQQQSHP HQHQHHPHPH PHPHHPHQLH GMGEQPPLPP  60
   61 PPPPLPHGML PPQPPMGPPM GVAGGQDATM SGKSHKPKKP HGSAPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1130-1248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQDTATRKQH QPLSAISIQD LNSVQLRRTD TQKVPKPYQM PARSLSMQCL TSSTETYLKS  60
   61 DLIAELKISK DIPGIKKMKV EQQMASRMDS EHYMEITKQF SGNNYVDQIY LQIPERDQA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1249-1299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNAIPDWKRQ MMAKKAAERA KKDFEERMAQ EAESRRLSQI PQWKRDLLAR R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1300-1436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EETENKLKAA IYTPKVEENN RVADTWRLKN RAMSIDNINI NLAGMEQHYQ QIQFQQKQQQ  60
   61 LQLGNKENHV DPKGADQDQE HGVGIGSGVG NANSGVIGGQ ELIDPSEGSQ GRAEEEEDNI 120
  121 IPWRAQLRKT NSRLSLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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