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View Structure Prediction Details

Protein: xmas-2-PA
Organism: Drosophila melanogaster
Length: 1370 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for xmas-2-PA.

Description E-value Query
Range
Subject
Range
gi|114684837 - gi|114684837|ref|XP_525497.2| PREDICTED: minichromosome maintenance protein 3 associated protein iso...
791.0 [0..13] [1231..436]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPRPGGYN YKTLLCRNIP ELFLDKYVAR SHFGRFGTLV NFVLRPRRMT CTVSYASEDE  60
   61 AARALLDGAS FQGHLFDISY ADNETAPAQK TEEWVDPDIQ AELSALQSGW RNEYGSGKPI 120
  121 K

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.14
Match: 1whxA
Description: Solution structure of the second RNA binding domain from hypothetical protein BAB23448
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.07267754227671 bayes_pls_golite062009
binding 2.14220509119821 bayes_pls_golite062009
mRNA binding 1.8272533737271 bayes_pls_golite062009
protein binding 0.825412428838605 bayes_pls_golite062009
nucleic acid binding 0.698120867472476 bayes_pls_golite062009
single-stranded RNA binding 0.0341340403989611 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [122-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQNGSSGSG GSSMLPAIPV GPATAPVSRD RTPAQLRDLE NMMRRPAHTS EEKFSVLDAR  60
   61 DKLLRLNRTQ HKLSGATQGH CADMCPEKER VLREFQRQVA YYELQPGSDE LICHERALKQ 120
  121 YSRSSADQET PLPHELRNET ALHMTMSYLM HEIMDISERQ DPQSHM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [288-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDWFHFVWDR TRSIRKEITQ QELCSLGAVK LVEQCARFHI HCAARLVDAD PSVFDSKINA  60
   61 ENLTKCLQTL KYMYHDLRIK GVPCPKEAEF RGYIVLLNLA DANFLWDIGQ LPAELQSCPE 120
  121 VRQAIQFYLA LQDTNFVRFF QLLADKDTSY LSACILVNYF TRLRVLGLHR LIQAYRSPRK 180
  181 DEVSSLPLSY IAELLSFASE QEAADFVQHY GL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [500-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QINEAGRVVL SRMHTVETEY KLPRQYELVE VKRVKSVGEV VSGEPLPPRD LYLNHRPHNS  60
   61 FDDYGMLKSI AWTAKDQLAG MQQEEMQPQM PSQPPAVSKH SDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1dg3A
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [603-959]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFKVPMQPDG TAAGFGVFAA AAVPPASSID GFSFVLPKSR AQEFQEQAPA TQQRRAQEEA  60
   61 KHQALQVAIA AAKKREAELM AIHEAKVAEA ERVRQQKLRE RQEQQRRQQQ ELEEQRQREQ 120
  121 EKLQLEKERQ LKLEQLFFVQ QQEREAHKQT RTLELYQEIF QDTLAEICQS EFMSHSRACR 180
  181 SYESMLDSIT RDLVERQMEQ SIYELGVMRV CIRRWRKYRR TQQEKDTLFN QLPLSFGAEN 240
  241 PEGVVNKRSM EDSLRLSRRY RLGEPCDYGK LLAGLEEHSW LKLDLWHVLD KCLPVAQPGA 300
  301 RRFYKLLISL SGGQEGLQLN CDLDRGLLQQ PQSPDARFVD GGYIRGFSQG IGLSVMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.045757
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [960-1066]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRDDDHDWKA TDLAEANGII CLIGLDDIRL LPDRLKPLLQ ASRCHDVAVI VQHPANTAFV  60
   61 QPDIPLQELC LRSFNIFRLR KSGNNRQRLM IALESAVKFL AKATERK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 2dfsA
Description: No description for 2dfsA was found.

Predicted Domain #7
Region A:
Residues: [1067-1289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVGHLHQVET REYLLVNLGS ELFRRLKYAA EHDTAIRSDT QLNPQRCVDL FNEAVHRLQL  60
   61 VAGEDLSDWP QFPEELRVFV QPLPIESSLN TNRLEHFEPG WHLPERRQRI VQLLERCKLP 120
  121 KMPVLPRSSS LAEAQCQWVL DYAQISQQED CVEQIALQAI KILQYDTDDY LNFVEYLAGE 180
  181 RMQYILRQER NPPQGIVYNT KTLKRRFLSA WYYEFREPQI YEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1290-1370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPAEENAQML EKQPSSQAEV QQLDFDEITS KAEAVLKRFH QRQDERHTLR ELNRSHKSRK  60
   61 RRDASDHKHA SKHKRKRSKS K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle