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View Structure Prediction Details

Protein: kat80-PA, kat80-PB
Organism: Drosophila melanogaster
Length: 819 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kat80-PA, kat80-PB.

Description E-value Query
Range
Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
673.0 [0..11] [741..730]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALPRKLISK IYDIKAHDSR VTSLDLGETG RVLVTGGEDR NVNLWAIGQN ECFMSLTGHN  60
   61 RSIDCVRFAY KDNFVYSADD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.221849
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [81-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGIIRRWDLN SQKIYSTLNG HMKSVRTLDF NPSGEYVVSG SNDTTVRLWD VQNENNCIKV  60
   61 CRGHMSHVNS VKFSPDGLWI ASAGLEGSIL IWDIRKSKQI MEFIADPPVT AITCVQFH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 2ojhA
Description: No description for 2ojhA was found.

Predicted Domain #3
Region A:
Residues: [199-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFEFLLAAGR VDGTVSIYDL EHQQLVSQTT HFYGQAIRCI TFSDNGECLF VGSSSGISVI  60
   61 GWEPDRELDH IKSTWSSLAD MKVVNNKLIC GCHEIDTVSI NTISLDRVIP FYQPPNSLPN 120
  121 FKHNSTNRKS FTRGNQKFRL SVGGAKPAQV QEEHEGDKSG LSSPNYSLEV VNEAVLESAE 180
  181 TSPMSSLPPV HLASMAGSSA DLAPHHVVYG GAIDSALRQG KYSRVPDNMA SYGSSYGAID 240
  241 TRLMSLNEPS SLHKPDIYNL YPLDKNEEAD VQQLEFNLND SNPPILNNYD NYEMAEDFPV 300
  301 NQNLNYITNN YKPVPATSTI NASSKSIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1s4uX
Description: Crystal Structure analysis of the beta-propeller protein Ski8p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.86142918698875 bayes_pls_golite062009
acetyltransferase activity 3.85374902981345 bayes_pls_golite062009
acyltransferase activity 3.35098520158193 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31615347567536 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.14917998298348 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 3.00422709839505 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.0212765804548 bayes_pls_golite062009
dynactin binding 1.85146647785657 bayes_pls_golite062009
nucleic acid binding 1.4991068812591 bayes_pls_golite062009
transcription regulator activity 1.42548927439572 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
DNA binding 0.963493426709289 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
transcription factor activity 0.435575551078191 bayes_pls_golite062009
molecular transducer activity 0.367729389382533 bayes_pls_golite062009
signal transducer activity 0.367729389382533 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.350063170588591 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
kinase activity 0.338000962379752 bayes_pls_golite062009
transcription initiation factor activity 0.319410949467982 bayes_pls_golite062009
histone methyltransferase activity 0.311523647180993 bayes_pls_golite062009
transcription repressor activity 0.298055197418849 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
transcription factor binding 0.136928257321035 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
0.0248988265652406 bayes_pls_golite062009
myosin II binding 0.0145748031956598 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [527-573]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTTTTTLHKR TTNNMAGAKQ TSTGIFGGSK LSQVSSVSSM ELHKLDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1r5mA
Description: Crystal Structure Of The C-Terminal WD40 Domain Of Sif2
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [574-819]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMVLKKSSSS NVVNKNKRPM GSAQSQFSKE NNQQKNINVE IITKPPMRSR TTLDMRTSHQ  60
   61 AKTQEKQIHQ QQPMNNRIIM DDHDFDMLSR SHEAVLQELS NRQSSLDLLR HATRSHDVLG 120
  121 ALRQARSCGK SIFIDLLGAI LEKPSSWNLD FCMFVLPEIY ELLQSQHKFH FTRACDTLRI 180
  181 ILSNFLPTIQ ENLDSWAANG LGVDVTREDR QRKCAECQRW LLQIKNLPES THFGSTLSQL 240
  241 QNIIIF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle