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View Structure Prediction Details

Protein: Bap60-PA
Organism: Drosophila melanogaster
Length: 515 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Bap60-PA.

Description E-value Query
Range
Subject
Range
gi|89267384 - gi|89267384|emb|CAJ82676.1| SWI/SNF related, matrix associated, actin dependent regulator of chromat...
646.0 [0..9] [514..25]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQRFAPGQA PVQSRYQPPP PAPGMRPYPP PGASFPPRGF PLHPNTTQPV PGTANVAGVP  60
   61 GVPGVPGVPG PSLLQRAAQQ PGFQSSLRGT GAGGGGVGSG GGSKRSNESR SLGGGGSKSD 120
  121 FATAKKKKKL AEKILPQKVR DLVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.39794
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [145-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESQAYMDLLT FERKLDATIM RKRLDIQEAL KRPMKQKRKL RIFISNTFYP SKEPTNDGEE  60
   61 GAVASWELRV EGRLLEDGKG DPNTKIKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [233-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFSSFFKSLV IELDKELYGP DNHLVEWHRT HTTQETDGFQ VKRPGDRNVR CTILLLLDYQ  60
   61 PLQFKLDPRL ARLLGVHTQT RPVIISALWQ YIKTHKLQDA HEREYINCDK YLEQIFSCQR 120
  121 MKFAEIPQRL NPLLHPPDPI VINHFIESGA ENKQTACYDI DVEVDDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1uhrA
Description: Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.01592136607858 bayes_pls_golite062009
basal transcription repressor activity 3.31155980072144 bayes_pls_golite062009
transcription activator activity 3.16006262739093 bayes_pls_golite062009
binding 2.67987108623459 bayes_pls_golite062009
protein binding 2.63183933218658 bayes_pls_golite062009
transcription coactivator activity 2.58234407051051 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.32480271621458 bayes_pls_golite062009
transcription repressor activity 1.98538788872171 bayes_pls_golite062009
transcription factor binding 1.73032563380905 bayes_pls_golite062009
transcription cofactor activity 1.60414428986898 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.06026105710513 bayes_pls_golite062009
structural molecule activity 0.66106995897056 bayes_pls_golite062009
p53 binding 0.19984769109713 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [400-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNQMNSFLM STASQQEIQG LDTKIHETVD TINQMKTNRE FFLSFAKDPQ MFIHRWIISE  60
   61 TRDLKLMTDV AGNPEEERRA EFYYQPWTHE AVSRYFFTKV NQKRAELEQA LGIRNG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle