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View Structure Prediction Details

Protein: FBpp0305497, flw-PB
Organism: Drosophila melanogaster
Length: 330 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305497, flw-PB.

Description E-value Query
Range
Subject
Range
gi|91084329 - gi|91084329|ref|XP_972528.1| PREDICTED: similar to Serine/threonine-protein phosphatase alpha-1 isof...
381.0 [0..1] [330..8486]

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Predicted Domain #1
Region A:
Residues: [1-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDFDLNVDS LIQRLLEMRS CRTGKQVQMT EAEVRGLCLK SREIFLQQPI LLELEAPLII  60
   61 CGDIHGQYTD LLRLFEYGGF PPAANYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFLL 120
  121 RGNHECASIN RIYGFYDECK RRYNVKLWKT FTDCFNCLPV AAIIDEKIFC CHGGLSPDLQ 180
  181 GMEQIRRLMR PTDVPDTGLL CDLLWSDPDK DVQGWGENDR GVSFTFGVDV VSKFLNRHEL 240
  241 DLICRAHQVV EDGYEFFARR QLVTLFSAPN YCGEFDNAGG MMTVDDTLMC SFQILKPSEK 300
  301 KAKYLYSGMN SSRPTTPQRS APMLATNKKK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.0
Match: 1s70A
Description: Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 11.6417995308386 bayes_pls_golite062009
protein serine/threonine phosphatase activity 10.6440947462013 bayes_pls_golite062009
phosphatase activity 10.5525832502704 bayes_pls_golite062009
phosphoric ester hydrolase activity 10.3702645338723 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 9.02791306892273 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity 6.04386346716682 bayes_pls_golite062009
myosin phosphatase activity 5.31703100176823 bayes_pls_golite062009
hydrolase activity 3.13006743434485 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.68552051869632 bayes_pls_golite062009
kinase activity 1.67788383575784 bayes_pls_golite062009
structural molecule activity 1.5850868178597 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.57807175808088 bayes_pls_golite062009
protein kinase activity 1.4514460578232 bayes_pls_golite062009
binding 1.44538582463569 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
transferase activity 1.3407391509244 bayes_pls_golite062009
protein binding 1.33435965029646 bayes_pls_golite062009
transporter activity 1.24767072239634 bayes_pls_golite062009
molecular transducer activity 1.08090214431427 bayes_pls_golite062009
signal transducer activity 1.08090214431427 bayes_pls_golite062009
calmodulin binding 0.77173071932406 bayes_pls_golite062009
protein serine/threonine kinase activity 0.66803085638835 bayes_pls_golite062009
substrate-specific transporter activity 0.528189469950839 bayes_pls_golite062009
structural constituent of muscle 0.126411744957937 bayes_pls_golite062009

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