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View Structure Prediction Details

Protein: Mipp2-PA
Organism: Drosophila melanogaster
Length: 453 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Mipp2-PA.

Description E-value Query
Range
Subject
Range
gi|4105501 - gi|4105501|gb|AAD02435.1| multiple inositol polyphosphate phosphatase 2; MIPP2 [Drosophila melanogas...
309.0 [0..1] [453..1]

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Predicted Domain #1
Region A:
Residues: [1-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSQFYCLFL LLLHFFVGVT LSEEGECRRL NRADIEGRLS TKTPYRAIAN YDETPPKYAG  60
   61 CHPTRIWTII RHGTRNPSES VILQAQNRLS EIKKRILDQT KPPICTAELE KLRQWHWMHL 120
  121 NATEDEKLLV AEGEDELIEL AERMQRRFPD LLPELYNPEW YYFKYTATQR TLKSAESFAT 180
  181 GLFGRHRIHT VRYPPPLHED PVLRFYKGCG KWKTDVDKNP ETLVNARRFL AEPQMQSAVE 240
  241 QVRSSTRLPD LQPEDVQLMY TVCAFETAWH RPRHDSGSKS SYESVWCNFF DVAALEALEF 300
  301 FEDLEYYWND GYGYELTHRI ACPAIADMFA AISSSEETRQ RRANATLYFT HSGTLLKLLA 360
  361 HLGLARDNKP LTHKHFASER LWRTSQIDAF ATNLAFLRYD CDKGNPQVLV LHQERVVRLP 420
  421 GCPQDKDLCP LATLRRIYAN SVDHCDREKM CRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.522879
Match: 1ihpA
Description: STRUCTURE OF PHOSPHOMONOESTERASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatase activity 1.82804953813502 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.63930771076865 bayes_pls_golite062009
bisphosphoglycerate phosphatase activity 1.52983854005469 bayes_pls_golite062009
bisphosphoglycerate 3-phosphatase activity 1.52983854005469 bayes_pls_golite062009
catalytic activity 1.37714494241232 bayes_pls_golite062009
binding 1.07479440684025 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.01761355562415 bayes_pls_golite062009
kinase activity 0.891791120150528 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.803890819223102 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.57794482374484 bayes_pls_golite062009
protein binding 0.236742803345453 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle