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View Structure Prediction Details

Protein: snf-PA
Organism: Drosophila melanogaster
Length: 216 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for snf-PA.

Description E-value Query
Range
Subject
Range
gi|73991119 - gi|73991119|ref|XP_857629.1| PREDICTED: similar to U2 small nuclear ribonucleoprotein B isoform 5 [C...
150.0 [0..1] [216..36]
gi|109124838 - gi|109124838|ref|XP_001098206.1| PREDICTED: small nuclear ribonucleoprotein polypeptide A isoform 6 ...
146.0 [0..2] [216..5]
AGAP011637-PA - snRNP-U1-A: U2 small nuclear ribonucleoprotein A|protein_coding|3L:30460348:30460998:-1|gene:AGAP011...
gi|55235062, gi|... - gi|58394659|ref|XP_320869.2| AGAP011637-PA [Anopheles gambiae str. PEST], gi|55235062|gb|EAA00418.2|...
145.0 [0..1] [216..1]
gi|37748043 - gi|37748043|gb|AAH59527.1| Snrpb2 protein [Danio rerio]
143.0 [0..1] [216..10]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMLPNQTIY INNLNEKIKK EELKKSLYAI FSQFGQILDI VALKTLKMRG QAFVIFKEIG  60
   61 SASNALRTMQ GFPFYDKPMQ IAYSKSDSDI VAKIKGTFKE RPKKVKPPKP APGTDEKKDK 120
  121 KKKPSSAEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.154902
Match: 1fhtA
Description: RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
U1 snRNA binding 4.22094068431436 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [130-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNPNAQTEQP PNQILFLTNL PEETNEMMLS MLFNQFPGFK EVRLVPNRHD IAFVEFTTEL  60
   61 QSNAAKEALQ GFKITPTHAM KITFAKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 2u1aA
Description: RNA BINDING DOMAIN 2 OF HUMAN U1A PROTEIN, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
U1 snRNA binding 4.22094068431436 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle