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View Structure Prediction Details

Protein: Mnt-PA, Mnt-PC, ...
Organism: Drosophila melanogaster
Length: 582 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Mnt-PA, Mnt-PC, ....

Description E-value Query
Range
Subject
Range
gi|52789331, gi|... - gi|52789331|gb|AAH83010.1| LOC494839 protein [Xenopus laevis], gi|148227068|ref|NP_001088134.1| hypo...
206.0 [0..68] [351..9]

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Predicted Domain #1
Region A:
Residues: [1-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIGGIGVL LEAAQFLEQH EKLPQAGGGG GSALGVGVAL PQQQQQTVHC KSNSIINNNN  60
   61 SSQHNRNSSS SSNGIIATPP FTNGNGNGTV GVGNASAIFN VSVNANGNGL SNGHSSPRSQ 120
  121 LAAAATAHDY EYSAAGVANG HSEGRPHVSA ARDQQDHPQH QQHANHMQIQ QHYGYMRSNI 180
  181 GGVIYGLHKD SADSAASSAC GAGAGAAAVG MSIASSAPAA GSQLSAHHHT G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [232-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGGRRRTTSS NSNGAGTREV HNKLEKERRA QLKECYDLLK KVLPMGDEDR KKTSNLTILD  60
   61 TAHKYVNSLS HEVCEQEAKI EKLAKQKIEL QKRLKQLSLR RESPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [337-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDQQIIPQAD KAVCLATTAT TAPPTAASGH NGTTILFDAG NACATGQLTT VINKTNGGAT  60
   61 AAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [400-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKHNGNHTG GATTTLTPAM GIMTIKNGNG SNGNMLAISP TGGHNHQLHQ HHNGSPAGSP  60
   61 SGIGATTGAT ITRGSPTPST PSPSPSSSSS GVSLSTSFMG GSSSSSSSSS SSSSSSSSSS 120
  121 SSSPTQQQQI ITPTATARSV GLKFHGGAGA AVPAGGGSVN GFHQADKDRN YTFLRLSAGT 180
  181 TAQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.19
Match: 2es4D
Description: Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle