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View Structure Prediction Details

Protein: CG12206-PC, CG12...
Organism: Drosophila melanogaster
Length: 582 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG12206-PC, CG12....

Description E-value Query
Range
Subject
Range
GRS11_ORYSJ - Monothiol glutaredoxin-S11 OS=Oryza sativa subsp. japonica GN=GRXS11 PE=2 SV=2
GRS11_ORYSA - Monothiol glutaredoxin-S11 - Oryza sativa (Rice)
333.0 [0..110] [523..95]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAITSNVSR LEPMRGISII IESPEVATAT PPPATTTATA EAEAATKQVA PTAKSNSNTE  60
   61 MSLKSQAAGM LLAFGDTAAT AKDNLETSYD TAAKSTAAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-177]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETNKIYPQLL LRIGGEIAGA TASAEAAASA ATAAAATATS PTIISCNGEI AASQAAATAA  60
   61 DTAATLQHNN TVKIQIES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [178-271]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGQQRTLGKQ ISVVKLNEGV EEMQQHMCYL VDTSGQYSPC ETLDSGTGSD LENHPQQQQQ  60
   61 PQQVRSPQLE LHLQTTRLMV NEEADHKHSP LETP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [272-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVPKRAYSL TDDSEECDES SNSSLSCDSL HSGGLLPTTL LRDIRFRERA SGPLVTKING  60
   61 RPLQFETDGY YTFHVREHEN FRSFGSNSST EYEAQHFTDE QPGEDFVGFR DIRTAGKLAG 120
  121 NSTIKSAKGT VRGVKNRVRN GVATFLQLQQ PNVKNYMEKD VGKVVLYTTS MGIIRDTYAK 180
  181 CANVKKILRT LLIKFEERDI FMSVEYQQEM RERMQDETIR VPQLFVEGQL IGDANIVERL 240
  241 NESGELRQLL RPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.30103
Match: 1nm3A
Description: C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.142133664747919 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [525-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSIATAYTCQ TCGGYRMLPC PACNGSKKSM HRNHFTAEFV ALKCMNCDEV GLIKCPNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 1exkA
Description: Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.036672061154828 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle