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View Structure Prediction Details

Protein: tw-PA, FBpp0307386
Organism: Drosophila melanogaster
Length: 765 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tw-PA, FBpp0307386.

Description E-value Query
Range
Subject
Range
gi|85118928 - gi|85118928|ref|XP_965543.1| hypothetical protein NCU01912 [Neurospora crassa OR74A]
gi|32417248, gi|... - gi|32417248|ref|XP_329102.1| hypothetical protein [Neurospora crassa], gi|28927353|gb|EAA36307.1| hy...
644.0 [0..38] [765..67]

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Predicted Domain #1
Region A:
Residues: [1-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASVVKTPK CPRRGSVKDV AQNAPRTAPT SSKEANWNWW LLLATVFLVT FATRFYKVTE  60
   61 PDHICWDETH FGKMGSWYIN RTFFFDVHPP LGKMLIGLSG YLTGYNGTFP FEKPGDKYNE 120
  121 TRYQGMRYFC TTLGALIMPM GFDTVYDLTR SHEAALLAAA YLIFDVGLLT LNQYILLDPI 180
  181 LLFFMMASVW GMVKVSKSTA SGGSYGLRWW LWLFLTGTML SCTISVKFVG LFVVLLVGLH 240
  241 TATELWLILG DLGQPILETV KQLACRAITL IVWPVLLYIL FFYIHLSVLN RSGNGDGFYS 300
  301 SAFQSRLIGN SLYNA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [316-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMPRDVAYGS LVTIKNHKTG GGYLHSHHHL YPKGSGARQQ QVTTYTHKDE NNKWLIRPHN  60
   61 KPGPPKGKVQ ILRHGDLVRL THMATRRNLH SHNEPAPMTK KHLQVTGYGE LGLGDANDVW 120
  121 RVLIVGGKVN ETVHTVTSRL KFIHLLQNCA LTSSGKQLPK WGFEQQEVSC NPNVRDKNSQ 180
  181 WNVEDNEHKL MPSVSFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1t9fA
Description: Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dolichyl-phosphate-mannose-protein mannosyltransferase activity 7.33543412640964 bayes_pls_golite062009
mannosyltransferase activity 6.32966341675541 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.60661923349025 bayes_pls_golite062009
receptor activity 1.98562812678228 bayes_pls_golite062009
cation channel activity 1.66500687404195 bayes_pls_golite062009
ion channel activity 1.61859406934521 bayes_pls_golite062009
substrate-specific channel activity 1.57127083095499 bayes_pls_golite062009
passive transmembrane transporter activity 1.55374970486978 bayes_pls_golite062009
channel activity 1.55374970486978 bayes_pls_golite062009
inositol-1,4,5-trisphosphate receptor activity 1.54960024640698 bayes_pls_golite062009
binding 1.28645358261768 bayes_pls_golite062009
molecular transducer activity 1.01765765844557 bayes_pls_golite062009
signal transducer activity 1.01765765844557 bayes_pls_golite062009
transferase activity 0.981084601370981 bayes_pls_golite062009
calcium channel activity 0.85901349040585 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.802620463808905 bayes_pls_golite062009
catalytic activity 0.659936859803906 bayes_pls_golite062009
calcium-release channel activity 0.65133561512386 bayes_pls_golite062009
gated channel activity 0.53737429019655 bayes_pls_golite062009
ligand-gated ion channel activity 0.52162184692236 bayes_pls_golite062009
ligand-gated channel activity 0.52162184692236 bayes_pls_golite062009
protein binding 0.428075756729427 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [513-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYAPGFFARF LESHAVMLQG NAGLKPKEGE VTSRPWQWPI NYRGQFFSGS SYRIYLLGNP  60
   61 LIWWSNLVFL ALFVTVFLCN AVVQQRRAGF ARSAAQNQAQ VPDSETVAQD EESEHSTTDI 120
  121 CSCCTPAKEI VPKAVPSGSP EAPNPAQSLR AAAWLFLGWM 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [673-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHYLPFWAMG RVLYFHHYFP ALIFNSLLTG VMYNYILRVL PKWIHHVILG LVLSILVYSF  60
   61 AAFSPLAYGM SGPLANEPNS TMYNLKWLST WEF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle