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View Structure Prediction Details

Protein: G9a-PA
Organism: Drosophila melanogaster
Length: 1637 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for G9a-PA.

Description E-value Query
Range
Subject
Range
gi|115926458 - gi|115926458|ref|XP_001180763.1| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...
876.0 [0..601] [1598..12]

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Predicted Domain #1
Region A:
Residues: [1-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDFVELMNS MSSTFNSDCA TSTAEGGTLL NLNLAEDKTL KWRNLANNQF ASKEKKHKDK  60
   61 EEEERKEARN QEEIEDIKAL LADVVDAAAV KLEEEEAQNA EKVEPHTKCE IEEEGRKEME 120
  121 YDQDVAKQDS EMEKKQNGKA TSITVKMESN ERAEKHATEI ATTSTERWEN ESFKTEQQNK 180
  181 KAAEKEEEPI LAATQKLEAN AEPLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [206-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTRIEVAVAS PLVVSSASVK LAADATNQMR AATSAGAATL ADKNVQVSPG GTRRSRRTPR  60
   61 PIDTPTSVTD EHVQVENKKF GKSEQYTDCS SHLERFTLDD NTAIVRLQLK SEPDKPSLTA 120
  121 LSPEENSAPA PKRGRGRARK IRPDAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [352-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VETSEVILPC EDSLGEKKPG RKRKLPDEPI DQQQLSDLVV VKTEQEELGD APLGDVKRMR  60
   61 RSVRLGNRLH ADGSPWEEVK TEALHPQPSA ELSFAEVTSE ILPLAVLDEK TPPKKRGRKA 120
  121 KTPCVKLESE TSCGLPFANG NKKTNSSGGC ELQLPKRSKR RIKPTPKILE NDELRCEFET 180
  181 KHIERMTQWE SAAAVDGDFE TPTTGGNGSN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [562-663]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTSRQKSDK SDGSNFEGGP GHPAGTSAIK KRLFSKSQRD IENYGAAMLA KSKLPPCPDV  60
   61 EQFLNDIKAS RINANRSPEE RKLNKKQQRK LAKQKEKHLK HL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [664-834]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLQKNHRDEP SDNDSSNTDN EFFPTTRVQV GKPSVTLRVR NSVTKELPTT ATLKSRRNPV  60
   61 VQAAKLTRRI GARAAGEVTE AARASVPIST PDAEQLHSLD TSIQADVTPI RDLDMRPSTS 120
  121 RVSKFICLCQ KPSQYYARNA PDSSYCCAID HIDDQKIGCC NELSSEVHNL L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [835-1320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPSQRVSYMI LCDEHKKRLQ SHNCCAGCGI FCTQGKFVLC KQQHFFHPDC AQRFILSTSY  60
   61 EKELGDEEDQ GVKFSSPVLV LKCPHCGLDT PERTSTVTMK CQSLPVFLRT QKYKIKPARL 120
  121 TTSSHLTQFG TVENANTPGA TARNKGGLST AVTLSAASSP ASKTNGAQRG RAGTSNSNSR 180
  181 HALNSINFAQ LIPESVMNVV LRGHVVSASG RVTAEFTPRD MYYAVQNDDL ERVAEILAAD 240
  241 FNVLTPIREY LNGTCLHLVA HSGTLQMAYL LLCKGASSPD FVNIVDYELR TALMCAVMNE 300
  301 KCDMLNLFLQ CGADVAIKGP DGKTSLHIAA QLGNLEATQL IVDSYRTSRN ITSFLSFIDA 360
  361 QDEGGWTAMV WAAELGHTDI VSFLLNQDAD PNICDNDNNT VLHWSTLHND GLDTITVLLQ 420
  421 SGADCNVQNV EGDTPLHIAC RHSVTRMCIA LIANGADLMI KNKAEQLPFD CIPNEESECG 480
  481 RTVGFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.60916417202222 bayes_pls_golite062009
protein binding 1.64872738860757 bayes_pls_golite062009
transcription regulator activity 0.589753112911856 bayes_pls_golite062009
cytoskeletal protein binding 0.39098214168175 bayes_pls_golite062009
nucleic acid binding 0.156667528524505 bayes_pls_golite062009
DNA binding 0.139886855398905 bayes_pls_golite062009
transcription factor binding 0.11440400380364 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1321-1637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQMRSFRPLG LRTFVVCADA SNGREARPIQ VVRNELAMSE NEDEADSLMW PDFRYVTQCI  60
   61 IQQNSVQIDR RVSQMRICSC LDSCSSDRCQ CNGASSQNWY TAESRLNADF NYEDPAVIFE 120
  121 CNDVCGCNQL SCKNRVVQNG TRTPLQIVEC EDQAKGWGVR ALANVPKGTF VGSYTGEILT 180
  181 AMEADRRTDD SYYFDLDNGH CIDANYYGNV TRFFNHSCEP NVLPVRVFYE HQDYRFPKIA 240
  241 FFSCRDIDAG EEICFDYGEK FWRVEHRSCV GCRCLTTTCK YASQSSSTNA SPTNATTAPE 300
  301 NETGTLSSTN TEKIGHA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.69897
Match: 2o8jA
Description: No description for 2o8jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle