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View Structure Prediction Details

Protein: mav-PA
Organism: Drosophila melanogaster
Length: 701 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mav-PA.

Description E-value Query
Range
Subject
Range
gi|17944333 - gi|17944333|gb|AAL48059.1| RE69013p [Drosophila melanogaster]
758.0 [0..1] [689..1]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIDINPNLT PKKETAVWCD SFQHKCKVSN RTIKIFPSLL NKSNWIVSIL WHICVHHTIT  60
   61 IRNSKAREPP CKHPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [76-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITDNAEAKLT LVCSRSLKLY KIWFILILLM STQHQVSGHG IFRQTSSSKA VFSYYQPKEN  60
   61 ITFTNLQLQN LENEAKRLET NQHPIIRAKS TPKMGLKNVF ESFSKQSRDS IYNASSNKYS 120
  121 LINVSQSKNF PQLFNKKLSV QWINTVPIQS RQTRETRDIG LETKRHSKPS KRVDETRLKH 180
  181 LVLKGLGIKK LPDMRKVNIS QAEYSSKYIE YLSRLRSNQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKGNSYFNNF MGASFTRDLH FLSITTNGFN DISNKRLRHR RSLKKINRLN QNPKKHQNYG  60
   61 DLLRGEQDTM NILLHFPLTN AQDANFHHDK IDEA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [389-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVRLMLLYSS SLATNFRRGP GSRKNKISQI SGNDNIERHC NFGDVNLNQS NKNSSQQLTL  60
   61 KVYQLLSANR RRKITSRKIE FGNVGFQETR TQWIEFDVTK AVRSWLNKSH ENLGIEIQCD 120
  121 KCKSIGARIL SDFSPST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [526-701]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPRSTASSDE HLNLMPVLNI IGHGTLNSQQ HGDADIHQIM LTNNRSDQYV HHRSNHDSTW  60
   61 RKDKWTNNCY KLHQRCCRNQ LDVAFKSIKG FEFILQPKVF DAGYCHGRCP PRHNPAHHHA 120
  121 LLQSLIWQED HKRAPRPCCT PSKLEMLEIL HVDENHSDKL KISTWSDMQV VECACS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.221849
Match: 1bmpA
Description: BONE MORPHOGENETIC PROTEIN-7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor serine/threonine kinase binding 2.59151978891498 bayes_pls_golite062009
transforming growth factor beta receptor binding 2.37742979972948 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 2.37742979972948 bayes_pls_golite062009
receptor binding 2.35731964024213 bayes_pls_golite062009
binding 1.94128368349087 bayes_pls_golite062009
protein binding 1.64946640536226 bayes_pls_golite062009
growth factor activity 1.46380647398443 bayes_pls_golite062009
growth factor binding 0.115424337995679 bayes_pls_golite062009
vascular endothelial growth factor receptor binding 0.0947383314256207 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle