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View Structure Prediction Details

Protein: mod-PA, FBpp0301951
Organism: Drosophila melanogaster
Length: 542 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mod-PA, FBpp0301951.

Description E-value Query
Range
Subject
Range
gi|76633747 - gi|76633747|ref|XP_881817.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
287.0 [0..166] [532..2]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKKAVTVK GKKATNGEEK PLAKRVTKST KVQEEETVVP QSPSKKSRKQ PVKEVPQFSE  60
   61 EDESDVEEQN DEQPGDDSDF ETEEAAGLID DEAEEDEEYN SDDEEDDDDD ELEPGEVSKS 120
  121 EGADEVDESD DDEEAPVEKP VSKKSEKANS EKSEENRGIP KVKVGKI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [168-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLGTPKNQIV FVTNLPNEYL HKDLVALFAK FGRLSALQRF TNLNGNKSVL IAFDTSTGAE  60
   61 AVLQAKPKAL TLGDNVLSVS Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.522879
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.2072391084044 bayes_pls_golite062009
nucleic acid binding 2.34356093608328 bayes_pls_golite062009
mRNA binding 2.19775829895338 bayes_pls_golite062009
RNA binding 1.69266495798651 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [249-542]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRNKEENNER TVVVGLIGPN ITKDDLKTFF EKVAPVEAVT ISSNRLMPRA FVRLASVDDI  60
   61 PKALKLHSTE LFSRFITVRR ISQESISRTS ELTLVVENVG KHESYSSDAL EKIFKKFGDV 120
  121 EEIDVVCSKA VLAFVTFKQS DAATKALAQL DGKTVNKFEW KLHRFERSTS GRAILVTNLT 180
  181 SDATEADLRK VFNDSGEIES IIMLGQKAVV KFKDDEGFCK SFLANESIVN NAPIFIEPNS 240
  241 LLKHRLLKKR LAIGQTRAPR KFQKDTKPNF GKKPFNKRPA QENGGKSFVK RARF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 2ghpA
Description: No description for 2ghpA was found.

Predicted functions:

Term Confidence Notes
binding 3.2072391084044 bayes_pls_golite062009
nucleic acid binding 2.34356093608328 bayes_pls_golite062009
mRNA binding 2.19775829895338 bayes_pls_golite062009
RNA binding 1.69266495798651 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle