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View Structure Prediction Details

Protein: Prosalpha3T-PA
Organism: Drosophila melanogaster
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prosalpha3T-PA.

Description E-value Query
Range		 Subject
Range
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 260.0 [0..3] [239..8]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p...
PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1
 258.0 [0..3] [239..8]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ...
PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1
 256.0 [0..3] [240..8]
gi|145020008, gi... - gi|39946336|ref|XP_362705.1| conserved hypothetical protein [Magnaporthe grisea 70-15], gb|EAA57374....
gi|59802961 - gi|59802961|gb|AAX07682.1| proteasome subunit alpha type 4-like protein [Magnaporthe grisea]
 256.0 [0..1] [248..1]
PSA_THEK1 - Proteasome subunit alpha OS=Thermococcus sp. (strain JCM 11816 / KS-1) GN=psmA PE=3 SV=1
PSA_THEK1, PSMA_... - Proteasome subunit alpha OS=Thermococcus sp. (strain KS-1) GN=psmA PE=3 SV=1, Proteasome subunit alp...
gi|11265988 - pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
 256.0 [0..3] [242..8]
gi|65304454 - gi|65304454|emb|CAI76833.1| proteasome subunit, putative [Theileria annulata]
gi|84997473 - gi|84997473|ref|XP_953458.1| proteasome subunit [Theileria annulata strain Ankara]
 255.0 [0..1] [245..1]
PSMA_PYRKO - Proteasome subunit alpha OS=Pyrococcus kodakaraensis GN=psmA PE=3 SV=1
PSA_THEKO - Proteasome subunit alpha OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=ps...
 255.0 [0..3] [242..8]
gi|68351418 - gi|68351418|gb|EAN32181.1| proteasome subunit alpha type, putative [Theileria parva]
gi|71029642 - gi|71029642|ref|XP_764464.1| proteasome subunit alpha type [Theileria parva strain Muguga]
 254.0 [0..1] [245..1]
gi|111058979 - gi|111058979|gb|EAT80099.1| hypothetical protein SNOG_12286 [Phaeosphaeria nodorum SN15]
 254.0 [0..1] [248..1]
PSA4A_ARATH - Proteasome subunit alpha type-4-A OS=Arabidopsis thaliana GN=PAC1 PE=1 SV=1
 253.0 [0..1] [246..1]

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Predicted Domain #1
Region A:
Residues: [1-251] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARFFDSRTT IFSPEGRLYQ VEYAMEAASQ SGTCVGLLAK NGVLLATERS VDKLMDTSIP  60
   61 VPRISWLNEN IACCATGNTA DGNVLVNQLR MIAQQYQFNF GEMIPCEQLV TNLCDIKQAY 120
  121 TQYGGKRPFG VSFLYMGWDC RFGFQLYQSD PSGNYSGWKA TCIGRKSGAA MEMLQKELFS 180
  181 KGYVSPSVEE AKDVAIKVMG MTLGRDSLTP EKLEIAFVQR YGNTTVFHIL EKNEIHRLIE 240
  241 RNNNLKRRVG S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.045757
Match: 1iruC
Description: Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 0.982918122186083 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle