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View Structure Prediction Details

Protein: CG31012-PC
Organism: Drosophila melanogaster
Length: 882 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31012-PC.

Description E-value Query
Range
Subject
Range
gi|33589274 - gi|33589274|gb|AAQ22404.1| SD08724p [Drosophila melanogaster]
289.0 [0..1] [882..1]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENNICAIVE YEYAAKEPDE LDLQKGAIIH RIKQMPGGWW QGTLKASGVT GMFPDNFVRV  60
   61 LESGVSSNGN GTTGSGDHIE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 1uecA
Description: p47pox (neutrophil cytosolic factor 1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [81-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGTAVQLRDK SATSNRRCKV IYSYTQVNDD ELTLAVGDVI EFLGEVEEGW WRGRLRSKVG  60
   61 VFPSNFVQHI EPSPVLASKR PPTIGATVTT SALTSKAANV ANVAATATVP TGGAVPPAST 120
  121 SISTSTTKQA TKSRATAAAA ASAPAEPAAI VSGSGAAAGG GAAAAVPMLP PKPQREFCRV 180
  181 EFPYAPQNDD ELELKVDDII AVISTELPDK GWWKGEIRGK VGVFPDNFVK MLAPSEVAPI 240
  241 NE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.375837873453985 bayes_pls_golite062009
protein binding 0.25580402341401 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [323-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSATQITQN QRKVSNTAST TSHMTTTNSS NSSTTSVTTQ QQKEQIGGSS STTSKVYIKK  60
   61 TGSSSNSTTS STTTASSSAG RKESFGSRDS LNDILSETGL PTGNVAAQRK SLENKNLDLT 120
  121 KPPGVGASVS IGQQRSSTSS ATTSSATTVA TGLTSSSVSK SMENMLDEKV KSPPPPVLSK 180
  181 KPSVPLKKTP TGGVPMTGNL LGGKKKNTEG KLTTAVSHDL ADGLAASKML SGANQLPESG 240
  241 AAGNVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [569-806]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRRAATIAVE DTDFDRVERA SILTDMRQGR VKAPKRRPPS AAINVLGESN NNSVYVNGSG  60
   61 MSGSGGAGSA SELSEDGGAG GKTSDDNSTG EEPQLAKPKP REWEKKKAPW MEELKASQVT 120
  121 RKKTSPSVEP RGASVAERTS KLFAAEQAVS SNSSSITTKV QSSAVTSSMF VENSTTSSSV 180
  181 ITSSSHTTTN DAIMSRSLSA AKVQTASSDE ETRATRPNSL AIRNQRSVSP LVKSSNAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [807-882]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSQSQEEKPT SQLNNHQDAS SSRVAQLEQR VDKLEGLVLN QQRTIEELVN ALKSEAERVK  60
   61 ILRSELDKYA QCVTQV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle