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View Structure Prediction Details

Protein: Jon99Fii-PA
Organism: Drosophila melanogaster
Length: 267 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Jon99Fii-PA.

Description E-value Query
Range
Subject
Range
gi|56199562 - gi|56199562|gb|AAV84270.1| serine protease [Culicoides sonorensis]
222.0 [0..1] [265..1]
gi|87130885 - gi|87130885|gb|ABD24064.1| intein-trypsinogen fusion protein [synthetic construct]
221.0 [0..30] [263..156]
gi|109074664 - gi|109074664|ref|XP_001109114.1| PREDICTED: transmembrane protease, serine 11D [Macaca mulatta]
221.0 [0..15] [265..164]
gi|114594518 - gi|114594518|ref|XP_001163735.1| PREDICTED: transmembrane protease, serine 11D isoform 1 [Pan troglo...
220.0 [0..15] [265..167]
gi|57160807, gi|... - gi|57162224|emb|CAI39655.1| protease, serine, 3 [Homo sapiens], gi|57160807|emb|CAI39514.1| protease...
220.0 [0..1] [263..1]
TRY2_RAT - Anionic trypsin-2 OS=Rattus norvegicus GN=Prss2 PE=1 SV=2
219.0 [0..1] [263..1]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLFVFLALA VAAATAIPTP EQKLVPTPVK DVKIQGRITN GYPAYEGKVP YIVGLLFSGN  60
   61 GNWWCGGSII GNTWVLTAAH CTNGASGVTI NYGASLRNQP QYTHWVGSGN FVQHHHYNSG 120
  121 NLHNDISLIR TPHVDFWHLV NKVELPSYND RYQDYAGWWA VASGWGGTYD GSPLPDWLQA 180
  181 VDVQIMSQSD CSRSWSLHDN MICINTNGGK STCGGDSGGP LVTHEGNRLV GVTSFVSSAG 240
  241 CQSGAPAVFS RVTGYLDWIR DNTGISY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 1hylA
Description: HL collagenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.91209560688646 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.52773635813967 bayes_pls_golite062009
serine hydrolase activity 5.5105092190926 bayes_pls_golite062009
serine-type peptidase activity 5.49703869306079 bayes_pls_golite062009
serine-type endopeptidase activity 5.39623690248556 bayes_pls_golite062009
endopeptidase activity 5.32070018460528 bayes_pls_golite062009
hydrolase activity 4.40346950809697 bayes_pls_golite062009
fucose binding 2.48666002776941 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009
protein binding 1.30414885212044 bayes_pls_golite062009
calcium-dependent protein binding 1.10244132298625 bayes_pls_golite062009
binding 0.878047845310622 bayes_pls_golite062009
receptor binding 0.79054390509229 bayes_pls_golite062009
glycosaminoglycan binding 0.56945513804111 bayes_pls_golite062009
nucleic acid binding 0.44829966204274 bayes_pls_golite062009
thrombospondin receptor activity 0.126941350425071 bayes_pls_golite062009
polysaccharide binding 0.0828866805581887 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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