YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Sry-delta-PA
Organism: Drosophila melanogaster
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sry-delta-PA.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
661.0 [0..2] [432..2434]

Back

Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTCFFCGAV DLSDTGSSSS MRYETLSAKV PSSQKTVSLV LTHLANCIQT QLDLKPGARL  60
   61 CPRCFQELSD YDTIMVNLMT TQKRLT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.992
Match: 1pzwA
Description: Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.84932768708444 bayes_pls_golite062009
DNA binding 3.45124926204188 bayes_pls_golite062009
nucleic acid binding 3.34875987514951 bayes_pls_golite062009
binding 2.8684204787273 bayes_pls_golite062009
transcription factor activity 2.74592237402384 bayes_pls_golite062009
transcription activator activity 1.45965791386122 bayes_pls_golite062009
sequence-specific DNA binding 1.44741411126911 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.32499836066598 bayes_pls_golite062009
protein binding 1.30321965120678 bayes_pls_golite062009
transcription factor binding 1.22761682002 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.1269808729848 bayes_pls_golite062009
structural constituent of ribosome 1.0478696280786 bayes_pls_golite062009
structural molecule activity 0.958501322313092 bayes_pls_golite062009
transcription cofactor activity 0.449959641856445 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.446369866668139 bayes_pls_golite062009
transcription repressor activity 0.199267983374872 bayes_pls_golite062009
catalytic activity 0.133319360419662 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLKGALKSE FEVPESGEDI LVEEVEIPQS DVETDADAEA DALFVELVKD QEESDTEIKR  60
   61 EFVDEEEEED DDDDDEFICE DVDVGDSEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [176-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYGKSSDGED RPTKKRVKQE CTTCGKVYNS WYQLQKHISE EHSKQPNHIC PICGVIRRDE  60
   61 EYLELHMNLH EGKTEKQCRY CPKSFSRPVN TLRHMRMHWD KKKYQCEKCG LRFSQDNLLY 120
  121 NHRLRHEAEE NPIICSICNV SFKSRKTFNH HTLIHKENRP RHYCSVCPKS FTERYTLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.522879
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #4
Region A:
Residues: [354-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHMKTHEGDV VYGVREEAPA DEQQVVEELH VDVDESEAAV TVIMSDNDEN SGFCLICNTN  60
   61 FENKKELEHH LQFDHDVVLK 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.06
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47951889934838 bayes_pls_golite062009
nucleic acid binding 4.35187767955595 bayes_pls_golite062009
DNA binding 4.31051339571017 bayes_pls_golite062009
transcription factor activity 3.28758716579796 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.05542379535543 bayes_pls_golite062009
transcription activator activity 1.97757778483124 bayes_pls_golite062009
transcription repressor activity 1.44763794968807 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
chromatin binding 1.26688155139311 bayes_pls_golite062009
transcription factor binding 1.23738346570539 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.776754909146767 bayes_pls_golite062009
transcription cofactor activity 0.627794176881836 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle