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View Structure Prediction Details

Protein: dmrt99B-PA
Organism: Drosophila melanogaster
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dmrt99B-PA.

Description E-value Query
Range
Subject
Range
gi|115583672, gi... - gi|124001512|dbj|BAF45379.1| polycystic kidney disease 1 like 3 [Mus musculus], gi|115583672|ref|NP_...
166.0 [0..55] [508..123]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPSGVDMQ NLMSQHPVLG ALPPAFFLRA ASERYQRTPK CARCRNHGVV SALKGHKRYC  60
   61 RWRDCVCAKC TLIAERQRVM AAQVALRRQQ AQEENEAREL GL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1lpvA
Description: DM domain of Doublesex (dsx)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.01128232423451 bayes_pls_golite062009
nucleic acid binding 0.127098718479447 bayes_pls_golite062009
DNA binding 0.0686553590152803 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [103-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYTSVPGQQN GSDSATPTPH SPNHSGSGGS GSGGSGQNGV FHGGIPSPPS DGFEASSTPN  60
   61 HHQQSQQQQQ AHHQQHLSHP HQQSQRFNGN ESDTDGRTRS EHLSVGFSPT 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [213-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTELDESPVS KRGAALSNET DQDTGSESGS PSSPRPKVAG LFNLTASLSP ARTGPPSSPE  60
   61 SDLDVDSAPD EATPENLSLK KEDSQSPPNT PAENLHLLRS FSSSHAQGFL PYHHTQFLAA 120
  121 AGLPAHHHPA AHSPHHQQQQ QQQQQQQNHL PQHHQQQQQQ QQQQQRSPID VLMRVFPNRR 180
  181 RSDVEQLMQR FRG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.961
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #4
Region A:
Residues: [406-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVLQAMECML AGEDLGQTPP QVPPSPPFPM KSAFSPLVPP SVFGSPTHRY HPFMQAHAKR  60
   61 FLTAPYAGTG YLPGVLSAAD IEQSESNGAG GIGLDRTSNA GDSQD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle