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View Structure Prediction Details

Protein: Ets97D-PA
Organism: Drosophila melanogaster
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ets97D-PA.

Description E-value Query
Range
Subject
Range
gi|7943, gi|4810... - gi|7943|emb|CAA48327.1| elg [Drosophila melanogaster], gi|544235|sp|Q04688|ELG_DROME DNA-binding pro...
500.0 [0..1] [464..1]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSSNDLSDE LIRRLSVGGA LEEVIASEMF EDSIDVETEA EPDDIIIVHM DIREPLSMLK  60
   61 SLVEQKIGVC LNYYTFWLQD AQELESHKNL VDQCVKGEGL VQINVQIQTI RKRINIADVL 120
  121 KPTEAALAAL AEEVVGQLSP 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1wjuA
Description: Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.78014377544701 bayes_pls_golite062009
binding 2.70872150536621 bayes_pls_golite062009
transcription regulator activity 2.23822335492051 bayes_pls_golite062009
nucleic acid binding 2.02209816078273 bayes_pls_golite062009
DNA binding 1.8833926783115 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.624731467637361 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [141-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PETASQKSSS SESPIKTPLK RMHKEDSEEE SVEGKDVKPV LNWVLDSKFK REQIRLKIPE  60
   61 AANEWTHAHV TYWLEWAVKQ FELVGINMSD WQMNGQELCA MTHEEFNQKL PRDPGNIFWT 120
  121 HLQLLKECNF VSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.045757
Match: 2jv3A
Description: No description for 2jv3A was found.

Predicted Domain #3
Region A:
Residues: [274-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHKRAEEQRK PKQPRIMSAN SISTNSGGSL SLEQRIMRKS YQSVKSSDSV ESTTSSMNPS  60
   61 NYTTIGSGNN GQVQLWQFLL EILTDCEHTD VIEWVGTEGE FKLTDPDRVA RLWGEKKNKP 120
  121 AMNYEKLSRA LRYYYDGDMI SKVSGKRFAY KFDCDLKLLI GYDANELSTL VSEGKTAPER 180
  181 VAATETITED T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1mdmB
Description: ETS-1 transcription factor, residues 331-440
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription repressor activity 3.85678231380989 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
specific transcriptional repressor activity 0.96257232341735 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
transcription corepressor activity 0.322180400748724 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle