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View Structure Prediction Details

Protein: msi-PA
Organism: Drosophila melanogaster
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for msi-PA.

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
441.0 [0..28] [592..4]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHALQEGATV LHHQQPPPPT SGEDHLLTAD SFFYARSNPM ENAAAAAAAA AAGLIDPHHN  60
   61 RDLHQALVAS IANNSVAAIG GGLTTAAVLK SAAQQSQQAV QQNQNAVVVT PGLEQPKQEP 120
  121 AQQAALALLK ENVNASAGAG QNNGQAAMGG SNKSGSSGRS TPSLSGGSGS DPAPGKLFVG 180
  181 GLSWQTSSDK LKEYFNMFGT VTDVLIMKDP VTQRSRGFGF ITFQEPCTVE KVLKVPIHTL 240
  241 DGKKIDPKHA TPKNRPRQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.39794
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.75748736237159 bayes_pls_golite062009
nucleic acid binding 2.9003829560934 bayes_pls_golite062009
mRNA binding 2.67679675039933 bayes_pls_golite062009
binding 2.30438455421982 bayes_pls_golite062009
0.61507045441317 bayes_pls_golite062009
single-stranded RNA binding 0.61170301639809 bayes_pls_golite062009
protein binding 0.403675976995418 bayes_pls_golite062009
transcription regulator activity 0.214300208089751 bayes_pls_golite062009
mRNA 5'-UTR binding 0.18283446592068 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.0860748299027598 bayes_pls_golite062009
poly-pyrimidine tract binding 0.0800614106161897 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [260-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKTKKIFVGG VSQDTSAEEV KAYFSQFGPV EETVMLMDQQ TKRHRGFGFV TFENEDVVDR  60
   61 VCEIHFHTIK NKKVECKKAQ PKEAVTPAAQ LLQKRIMLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 2go9A
Description: No description for 2go9A was found.

Predicted Domain #3
Region A:
Residues: [359-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLGVQLPTAP GQLIGARGAG VATMNPLAML QNPTQLLQSP AAAAAAQQAA LISQNPFQVQ  60
   61 NAAAAASIAN QAGFGKLLTT YPQTALHSVR YAPYSIPASA ATANAALMQA HQAQSVAAAA 120
  121 HHHQQQQQQQ HHHQQQTHNA HVAAAQQQQQ SHHNAVSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [517-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASQAHSAAA AAALAANAAN GAGAAGAHSL AAAAQQAGLM AGNPLNAAAA AAAAAANPAA  60
   61 AYSNYALANV DMSSFQGVDW STMYGMGMYV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

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