YRC Public Data Repository - Protein Structure Prediction

Protein:	veli-PA
Organism:	Drosophila melanogaster
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for veli-PA.

Description	E-value	Query Range	Subject Range
gi\|194111831, gi... - gi\|195151695\|ref\|XP_002016774.1\| GL21893 [Drosophila persimilis], gi\|194111831\|gb\|EDW33874.1\| GL2189... gi\|125775900\|ref... - GA20509-PA [Drosophila pseudoobscura], GA20509 [Drosophila pseudoobscura pseudoobscura] gi\|125775900, gi... - gi\|54638843\|gb\|EAL28245.1\| GA20509 [Drosophila pseudoobscura pseudoobscura], gi\|125775900\|ref\|XP_001...	171.0	[0..1]	[195..1]
gi\|109125456 - gi\|109125456\|ref\|XP_001114636.1\| PREDICTED: similar to lin-7 homolog B isoform 1 [Macaca mulatta]	167.0	[0..1]	[195..1]
LIN7B_BOVIN - Protein lin-7 homolog B OS=Bos taurus GN=LIN7B PE=2 SV=1	167.0	[0..1]	[195..1]
LIN7B_MOUSE - Protein lin-7 homolog B OS=Mus musculus GN=Lin7b PE=1 SV=2	167.0	[0..1]	[195..1]
gi\|109125454 - gi\|109125454\|ref\|XP_001114658.1\| PREDICTED: similar to lin-7 homolog B isoform 2 [Macaca mulatta] LIN7B - lin-7 homolog B (C. elegans) gi\|73947126 - gi\|73947126\|ref\|XP_851922.1\| PREDICTED: similar to lin-7 homolog B isoform 2 [Canis familiaris]	166.0	[0..1]	[195..1]
LIN7B_RAT - Protein lin-7 homolog B OS=Rattus norvegicus GN=Lin7b PE=1 SV=1	166.0	[0..1]	[195..1]
gi\|157107719, gi... - gi\|157107719\|ref\|XP_001649907.1\| hypothetical protein AaeL_AAEL004846 [Aedes aegypti], gi\|157107717\|...	165.0	[0..1]	[195..1]
gi\|55238674, gi\|... - gi\|58387886\|ref\|XP_315884.2\| ENSANGP00000017469 [Anopheles gambiae str. PEST], gi\|55238674\|gb\|EAA116...	165.0	[0..1]	[195..1]
gi\|50882515, gi\|... - gi\|52219174\|ref\|NP_001004672.1\| lin7c protein [Danio rerio], gi\|51859336\|gb\|AAH81422.1\| Lin-7 homolo...	164.0	[0..1]	[195..1]
gi\|91080051 - gi\|91080051\|ref\|XP_973222.1\| PREDICTED: similar to veli CG7662-PA [Tribolium castaneum]	163.0	[0..1]	[195..1]

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Predicted Domain #1

Region A:
Residues: [1-78]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNAEPLTL SRDVKRSIEL LEKLQASGDF PTTKLAALQK VLNSDFMTSV REVYEHVYET  60
   61 VDIQGSHDVR ASATAKAT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.47
Match:	1y74A
Description:	Solution Structure of mLin-2/mLin-7 L27 Domain Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
epidermal growth factor receptor binding	2.83728577240611	bayes_pls_golite062009
binding	1.72922707266313	bayes_pls_golite062009
protein binding	1.08813585723961	bayes_pls_golite062009
PDZ domain binding	0.950044269901752	bayes_pls_golite062009
receptor binding	0.684990774885903	bayes_pls_golite062009
protein domain specific binding	0.450006870427269	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [79-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAAFAASEGH AHPRVVELPK TEEGLGFNVM GGKEQNSPIY ISRIIPGGVA DRHGGLKRGD  60
   61 QLLSVNGVSV EGENHEKAVE LLKQAVGSVK LVVRYTPKVL EEMEMRFDKQ RNTRRRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.69897
Match:	2dkrA
Description:	No description for 2dkrA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: