YRC Public Data Repository - Protein Structure Prediction

Protein:	TfIIA-S-PA
Organism:	Drosophila melanogaster
Length:	106 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TfIIA-S-PA.

Description	E-value	Query Range	Subject Range
gi\|21064507 - gi\|21064507\|gb\|AAM29483.1\| RE44302p [Drosophila melanogaster]	174.0	[0..1]	[106..1]
gi\|66504876 - gi\|66504876\|ref\|XP_623063.1\| PREDICTED: similar to Transcription initiation factor IIA gamma chain (...	172.0	[0..1]	[105..1]
gi\|54638385, gi\|... - gi\|54638385\|gb\|EAL27787.1\| GA18701-PA [Drosophila pseudoobscura], gi\|125774789\|ref\|XP_001358646.1\| G...	170.0	[0..1]	[103..1]
gi\|114052188, gi... - gi\|95102994\|gb\|ABF51438.1\| transcription initiation factor IIA gamma chain [Bombyx mori], gi\|1140521...	169.0	[0..1]	[105..1]
gi\|118784309, gi... - gi\|118784309\|ref\|XP_313653.3\| ENSANGP00000013128 [Anopheles gambiae str. PEST], gi\|116128445\|gb\|EAA0...	168.0	[0..1]	[103..1]
gi\|91086493 - gi\|91086493\|ref\|XP_970803.1\| PREDICTED: similar to transcription initiation factor IIA gamma chain [...	167.0	[0..1]	[103..1]
gi\|157167547, gi... - gi\|157167547\|ref\|XP_001654850.1\| transcription initiation factor IIA (TFIIA), gamma chain [Aedes aeg...	167.0	[0..1]	[102..1]
gi\|74224980 - gi\|74224980\|dbj\|BAE38203.1\| unnamed protein product [Mus musculus]	164.0	[0..1]	[104..1]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQLYRNTT LGNTLQESLD ELIQYGQITP GLAFKVLLQF DKSINNALNQ RVKARVTFKA  60
   61 GKLNTYRFCD NVWTLMLNDV EFREVHEIVK VDKVKIVACD GKSGEF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.522879
Match:	1nvpD
Description:	HUMAN TFIIA/TBP/DNA COMPLEX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	10.9702263885595	bayes_pls_golite062009
RNA polymerase II transcription factor activity	5.06993130505706	bayes_pls_golite062009
transcription regulator activity	4.7915315980149	bayes_pls_golite062009
transcription activator activity	2.75298328621175	bayes_pls_golite062009
nucleic acid binding	2.26583234267697	bayes_pls_golite062009
DNA binding	2.12151270115091	bayes_pls_golite062009
transcription coactivator activity	2.10703866415858	bayes_pls_golite062009
binding	1.9212205923594	bayes_pls_golite062009
protein binding	1.54756881357956	bayes_pls_golite062009
transcription factor binding	1.31659763916181	bayes_pls_golite062009
transcription cofactor activity	1.15899255380593	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: