YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: orb-PD, orb-PB
Organism: Drosophila melanogaster
Length: 913 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for orb-PD, orb-PB.

Description E-value Query
Range
Subject
Range
orb-PA, FBpp0306565 - The gene oo18 RNA-binding protein is referred to in FlyBase by the symbol Dmel\orb (CG10868, FBgn000...
397.0 [0..78] [913..80]

Back

Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGVEKPYVV EPAMAVAQDS FEFGSNGDGS STNSHTSNAS SKDLGRLTSG DGAQNFAQDS  60
   61 SANSIDQDST DNTNSDCN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PITLNDLLGL CGASTANEVV GTGQTPSTSA PILGAGGGGR ANGVTAGAAT ATGVGVGAGG  60
   61 TLPGPGVPSI QGGGGGGVVG QQTNAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 2ihxB
Description: No description for 2ihxB was found.

Predicted Domain #3
Region A:
Residues: [165-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNTSAANPSA SFGGNGSSSD VNNLLLASAA AAAAAAAGDG AQLSANAAAY APLTPSSTHS  60
   61 SASPGTKSNF DYFQFENVAQ SNPLKAFQRT NI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [257-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDCSAPLSP STPTSIYNRS FHSSPLVSDS SNSSSGIGLS MDSINMFYNQ QQQQQQPEQQ  60
   61 GYTSLGNSMG SGLGLSLANA STRSNSPESQ NSSNSTTEQN LLDMINLLSV NSNKIPHQQQ 120
  121 QQQQQQQQQQ QQQQQNQQQL QVQQQHQLQQ QFVNLNRNYE QQISANLGSQ QHGFEHNGVG 180
  181 VGASSSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [444-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NENCFSQYNL ENITSVDMEL AKLQNLQRIN TLKLLHAQAQ QMPLINQLLQ SYAGNAIGSV  60
   61 GGSNLGNLMS AGGSSLMTEM AGNVGGIITT NDGHLDRVAK FYKSSAALCD ATCT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [558-782]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSGHLPPRSH RMLNYSPKVF LGGIPWDISE QSLIQIFKPF GSIKVEWPGK EQQAAQPKGY  60
   61 VYIIFESDKQ VKALLSACVL QVDDSHCGRN YFFKISSRRI KSKDVEVIPW IIADSNFVRS 120
  121 SSQKLDPTKT VFVGALHGKL TAEGLGNIMD DLFDGVLYAG IDTDKYKYPI GSGRVTFSNF 180
  181 RSYMKAVSAA FIEIRTTKFT KKVQVDPYLE DALCSICGVQ HGPYY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.154902
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
nucleic acid binding 3.64594243387558 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
binding 3.00411894202318 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
1.71820051628117 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 0.862661444935922 bayes_pls_golite062009
transcription regulator activity 0.737458867828906 bayes_pls_golite062009
DNA binding 0.691258294213766 bayes_pls_golite062009
mRNA 3'-UTR binding 0.599389001184667 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
sequence-specific DNA binding 0.366758605553422 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009
transcription activator activity 0.119266921032347 bayes_pls_golite062009
structural molecule activity 0.0829058000493267 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [783-913]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CRELSCFRYF CRSCWQWQHS CDIVKNHKPL TRNSKSQSLV GIGPSSSNVS LPFSGQRSIR  60
   61 DNRMGNGQHQ QHQQHQYQQQ KHRQLQEYSQ PHSLNVMGNS GAANAAATSM VTLQQRQIHK 120
  121 VRIQRQQHQA I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle