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View Structure Prediction Details

Protein: orb-PA, FBpp0306565
Organism: Drosophila melanogaster
Length: 915 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for orb-PA, FBpp0306565.

Description E-value Query
Range
Subject
Range
gi|8307, gi|103288 - gi|8307|emb|CAA45757.1| ovarian protein [Drosophila melanogaster], pir||S24577 ovarian protein - fru...
519.0 [0..1] [915..1]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLLQQYDTP DCSGSGGNMR ALSGGSTTEL LQKHSISSYL DHHHQQQQQQ QHHLQLQQHQ  60
   61 QQHSLLERCN DDGLISFIND PITLNDLLGL CGASTANEVV GTGQTPSTSA PILGAGGGGR 120
  121 ANGVTAGAAT ATGVGVGAGG TLPGPGVPSI QGGGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [156-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGVVGQQTNA SCNTSAANPS ASFGGNGSSS DVNNLLLASA AAAAAAAAGD GAQLSANAAA  60
   61 YAPLTPSSTH SSASPGTKSN FDYFQFENVA QSNPLKAFQR TNISFDCSAP LSPSTPTSIY 120
  121 NRSFHSSPLV SDSSNSSSGI GLSMDSINMF YNQQQQQQQP EQQGYTSLGN SMGSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [331-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGLSLANAST RSNSPESQNS SNSTTEQNLL DMINLLSVNS NKIPHQQQQQ QQQQQQQQQQ  60
   61 QQQNQQQLQV QQQHQLQQQF VNLNRNYEQQ ISANLGSQQH GFEHNGVGVG ASSSGNENCF 120
  121 SQYNLENITS VDMELAKLQN LQRINTLKLL HAQAQQMPLI NQLLQSYAGN AIGSVGGSNL 180
  181 GNLMSAGGSS LMTEMAGNVG GIITTNDGHL DRVAKFYKSS AALCDATCTW SGHLPP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1dv4A
Description: 30S subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [567-779]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSHRMLNYSP KVFLGGIPWD ISEQSLIQIF KPFGSIKVEW PGKEQQAAQP KGYVYIIFES  60
   61 DKQVKALLSA CVLQVDDSHC GRNYFFKISS RRIKSKDVEV IPWIIADSNF VRSSSQKLDP 120
  121 TKTVFVGALH GKLTAEGLGN IMDDLFDGVL YAGIDTDKYK YPIGSGRVTF SNFRSYMKAV 180
  181 SAAFIEIRTT KFTKKVQVDP YLEDALCSIC GVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.045757
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
nucleic acid binding 3.64594243387558 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
binding 3.00411894202318 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
1.71820051628117 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 0.862661444935922 bayes_pls_golite062009
transcription regulator activity 0.737458867828906 bayes_pls_golite062009
DNA binding 0.691258294213766 bayes_pls_golite062009
mRNA 3'-UTR binding 0.599389001184667 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
sequence-specific DNA binding 0.366758605553422 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009
transcription activator activity 0.119266921032347 bayes_pls_golite062009
structural molecule activity 0.0829058000493267 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [780-915]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGPYYCRELS CFRYFCRSCW QWQHSCDIVK NHKPLTRNSK SQSLVGIGPS SSNVSLPFSG  60
   61 QRSIRDNRMG NGQHQQHQQH QYQQQKHRQL QEYSQPHSLN VMGNSGAANA AATSMVTLQQ 120
  121 RQIHKVRIQR QQHQAI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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