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View Structure Prediction Details

Protein: burs-PA
Organism: Drosophila melanogaster
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for burs-PA.

Description E-value Query
Range
Subject
Range
gi|195143595, gi... - gi|195143595|ref|XP_002012783.1| GL23793 [Drosophila persimilis], gi|194101726|gb|EDW23769.1| GL2379...
gi|54637878|gb|E... - GA12271-PA [Drosophila pseudoobscura], GA12271 [Drosophila pseudoobscura pseudoobscura]
gi|125773769, gi... - gi|54637878|gb|EAL27280.1| GA12271 [Drosophila pseudoobscura pseudoobscura], gi|125773769|ref|XP_001...
172.0 [0..1] [173..1]
gi|164518956 - gi|164518956|ref|NP_001106757.1| apomucin [Sus scrofa]
gi|2581864, gi|7... - pir||T03099 mucin, submaxillary - pig, gi|2581864|gb|AAC62527.1| submaxillary apomucin [Sus scrofa d...
148.0 [0..11] [135..13152]
gi|51872651 - gi|51872651|tpg|DAA05596.1| TPA: TPA_inf: mucin apoprotein precursor [Rattus norvegicus]
143.0 [0..11] [136..3158]
gi|114431224 - gi|114431224|ref|NP_034974.1| mucin 5, subtypes A and C, tracheobronchial/gastric [Mus musculus]
140.0 [0..12] [171..2569]
gi|7513539, gi|3... - pir||T42233 submaxillary mucin 1 - bovine (fragment), gi|3057087|gb|AAC39250.1| bovine submaxillary ...
135.0 [0..11] [135..1449]
gi|113422699 - gi|113422699|ref|XP_001130382.1| PREDICTED: similar to Mucin-5AC (Mucin 5 subtype AC, tracheobronchi...
134.0 [0..13] [161..2961]
MUCAP_PIG - Apomucin (Fragment) OS=Sus scrofa PE=1 SV=2
134.0 [0..11] [135..1014]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRHLLRHEN NKVFVLILLY CVLVSILKLC TAQPDSSVAA TDNDITHLGD DCQVTPVIHV  60
   61 LQYPGCVPKP IPSFACVGRC ASYIQVSGSK IWQMERSCMC CQESGEREAA VSLFCPKVKP 120
  121 GERKFKKVLT KAPLECMCRP CTSIEESGII PQEIAGYSDE GPLNNHFRRI ALQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.82
Match: 1hcnB
Description: Gonadotropin B chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 3.35996116486789 bayes_pls_golite062009
cytokine activity 2.73712874200453 bayes_pls_golite062009
growth factor activity 2.6160729614164 bayes_pls_golite062009
vascular endothelial growth factor receptor 1 binding 2.34325173014763 bayes_pls_golite062009
binding 2.05370202030285 bayes_pls_golite062009
protein binding 1.82386610100131 bayes_pls_golite062009
transforming growth factor beta receptor binding 1.79811530491169 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 1.79811530491169 bayes_pls_golite062009
glycosaminoglycan binding 1.67510105131784 bayes_pls_golite062009
cell surface binding 1.66674781438071 bayes_pls_golite062009
vascular endothelial growth factor receptor binding 1.53869600764493 bayes_pls_golite062009
receptor serine/threonine kinase binding 1.52326054173375 bayes_pls_golite062009
heparin binding 1.23772590555078 bayes_pls_golite062009
vascular endothelial growth factor receptor 2 binding 1.13171867198032 bayes_pls_golite062009
growth factor binding 1.03019655218593 bayes_pls_golite062009
hormone activity 1.02692930083275 bayes_pls_golite062009
polysaccharide binding 0.999976313378305 bayes_pls_golite062009
pattern binding 0.777498464123891 bayes_pls_golite062009
platelet-derived growth factor receptor binding 0.670059401770955 bayes_pls_golite062009
type II transforming growth factor beta receptor binding 0.605794301244184 bayes_pls_golite062009
identical protein binding 0.598427754086431 bayes_pls_golite062009
protein dimerization activity 0.139996982599169 bayes_pls_golite062009
protein heterodimerization activity 0.129103245482061 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle