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View Structure Prediction Details

Protein: bap-PA
Organism: Drosophila melanogaster
Length: 382 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bap-PA.

Description E-value Query
Range
Subject
Range
gi|15823130 - gi|15823130|dbj|BAB68716.1| homeobox protein [Mus musculus musculus]
tr|Q920T7|Q920T7... - tr|Q920T7|Q920T7_MOUSE Homeobox protein (Fragment) OS=Mus musculus GN=Hoxa2 PE=2 SV=1, Homeobox prot...
145.0 [0..168] [381..6]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNMESAGVS AAMAGLSKSL TTPFSINDIL TRSNPETRRM SSVDSEPEPE KLKPSSDRER  60
   61 SISKSPPLCC RDLGLYKLTQ PKEIQPSARQ PSNYLQYYAA AMDNNNHHHQ ATGTSNSSAA 120
  121 DYMQRKLAYF GSTLAAPLDM RRCTSNDSDC DSPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSSSPSESP LSHDGSGLSR KKRSRAAFSH AQVFELERRF AQQRYLSGPE RSEMAKSLRL  60
   61 TETQVKIWFQ NRRYKTKRKQ IQQHEAALLG ASKRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1b72A
Description: Homeobox protein hox-b1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.20302368446064 bayes_pls_golite062009
DNA binding 3.910335137985 bayes_pls_golite062009
nucleic acid binding 3.70444192553266 bayes_pls_golite062009
transcription factor activity 3.41495638905535 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.0896307866191 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.72533206529661 bayes_pls_golite062009
transcription repressor activity 1.55910796763122 bayes_pls_golite062009
transcription activator activity 1.36535925881104 bayes_pls_golite062009
transcription factor binding 1.05399367242529 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.7265140277161 bayes_pls_golite062009
chromatin binding 0.572427333286789 bayes_pls_golite062009
transcription cofactor activity 0.49703800163515 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [250-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVQVLVREDG STTYAHMAAP GAGHGLDPAL INIYRHQLQL AYGGLPLPQM QMPFPYFYPQ  60
   61 HKVPQPIPPP TQSSSFVTAS SASSSPVPIP IPGAVRPQRT PCPSPNGQMM SVESGAESVH 120
  121 SAAEDVDENV EID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle