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View Structure Prediction Details

Protein: CG17838-PE
Organism: Drosophila melanogaster
Length: 571 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG17838-PE.

Description E-value Query
Range
Subject
Range
CG17838-PF - This gene is referred to in FlyBase by the symbol Dmel\CG17838 (CG17838, FBgn0038826). It is a prote...
355.0 [0..43] [571..1]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSQMEASKV QKDEGGGEAL SRTILKTPSS FRTPSPIPSC SKMAEGNGEL LDDINQKADD  60
   61 RGDGERTEDY PKLLEYGLDK KVAGKLDEIY KTGKLAHAEL DERALDALKE FPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1fxlA
Description: Hu antigen D (Hud)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [114-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGALNVLGQF LESNLEHVSN KSAYLCGVMK TYRQKSRASQ QGVAAPATVK GPDEDKIKKI  60
   61 LERTGYTLDV TTGQRKYGGP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [194-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPHWEGNVPG NGCEVFCGKI PKDMYEDELI PLFENCGIIW DLRLMMDPMT GTNRGYAFVT  60
   61 FTNREAAVNA VRQLDNHEIK PGKCLKINIS VPNLRLFVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2dguA
Description: No description for 2dguA was found.

Predicted Domain #4
Region A:
Residues: [293-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIPKSKGKDE ILEEFGKLTA GLYEVIIYSS PDDKKKNRGF CFLEYESHKA ASLAKRRLGT  60
   61 GRIKVWGCDI IVDWADPQEE PDEQTMSKVK VLYVRNLTQD VSEDKLKEQF EQYGKVERVK 120
  121 KIKDYAFIHF EDRDSAVEAM RGLNGKEIGA SNIEVSLAKP PSDK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.34
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.55209579427288 bayes_pls_golite062009
binding 2.12674248708253 bayes_pls_golite062009
nucleic acid binding 1.64322098035939 bayes_pls_golite062009
mRNA binding 1.10126462659919 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [457-571]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKEEILRAR ERRMMQMMQA RPGIVGNLSP THPSIMSLTP MRPGARMPLR TPIPREYVVG  60
   61 KRKFDGGHQN PADVKRRYPS GLIGNGGSWG SLPLPQQPLG TNGEQWYMDT FSAWS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle