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View Structure Prediction Details

Protein: CG17838-PD
Organism: Drosophila melanogaster
Length: 707 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG17838-PD.

Description E-value Query
Range
Subject
Range
gi|73976775 - gi|73976775|ref|XP_539581.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
353.0 [0..115] [704..14]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSQMEASKV QKDEGGGEAL SRTILKTPSS FRTPSPIPSC SKMAEGNGEL LDDINQKADD  60
   61 RGDGERTEDY PKLLEYGLDK KVAGKLDEIY KTGKLAHAEL DERALDALKE FPVDGALNVL 120
  121 GQFLESNLEH VSNKSAYLCG VMKTYRQKSR ASQQGVAAPA TVKGPDEDKI KKILERTGYT 180
  181 LDVTTGQRKY GGPPPHW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [198-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGNVPGNGCE VFCGKIPKDM YEDELIPLFE NCGIIWDLRL MMDPMTGTNR GYAFVTFTNR  60
   61 EAAVNAVRQL DNHEIKPGKC LKINISVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.09691
Match: 2dguA
Description: No description for 2dguA was found.

Predicted Domain #3
Region A:
Residues: [286-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLRLFVGNIP KSKGKDEILE EFGKLTAGLY EVIIYSSPDD KKKNRGFCFL EYESHKAASL  60
   61 AKRRLGTGRI KVWGCDIIVD W

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.30103
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [367-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADPQEEPDEQ TMSKVKVLYV RNLTQDVSED KLKEQFEQYG KVERVKKIKD YAFIHFEDRD  60
   61 SAVEAMRGLN GKEIGASNIE VSLAKPPSDK KKKEEILRAR ERRMMQMMQA RPGIVGNLSP 120
  121 THPSIMSLTP M

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.47
Match: 1whxA
Description: Solution structure of the second RNA binding domain from hypothetical protein BAB23448
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.55209579427288 bayes_pls_golite062009
binding 2.12674248708253 bayes_pls_golite062009
nucleic acid binding 1.64322098035939 bayes_pls_golite062009
mRNA binding 1.10126462659919 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [498-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPGARMPLRT PIPREYDYFY DFFGFSDYRQ GGSFGNNVSY YDDMYRWIDG DY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [550-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYYDYPNGGG GGSGGGGGSV SGGTVLPLSA GGSQNSPMAS GQRSARGSAS GPSASPSLMG  60
   61 VGRGHGITVP RGRVVGQRGS ISRLGAQTVP QAAGAAAAAG QAAAAVAQRG ATGQGAPAAT 120
  121 GGFRGVLPTR PSARGTQHVK PLQNLPAGAA FKTFMEGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle