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View Structure Prediction Details

Protein: ns1-PA
Organism: Drosophila melanogaster
Length: 581 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ns1-PA.

Description E-value Query
Range
Subject
Range
gi|21428328 - gi|21428328|gb|AAM49824.1| AT23067p [Drosophila melanogaster]
345.0 [0..1] [581..1]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALKRLKTKK SKRLTGRLKH KIEKKVRDHN KKERRAAKKN PKKGSKKQKL IQIPNICPFK  60
   61 DDILKEVEEA KQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.013228
Match: PF08701.2
Description: No description for PF08701.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQEAERLARR EAFKAEREQN KFKTLESMVE DADMRSTVHG IMHENDAQDQ DEKKYKNAVT  60
   61 KEQSLKQYFK EFRKVIENAD VVLEVVDARD PLGTRCNEVE RAVRGAPGNK RLVLVLNKAD 120
  121 LVPRENLNNW IKYFRRSGPV TAFKASTQDQ ANRLGRRKLR EMKTEKAMQG SVCIGAELLM 180
  181 SMLGNYCRNK GIKTSIRVGV VGIPNVGKSS IINSLTRGRS CMVGSTPGVT KSMQEVELDS 240
  241 KIKLIDCPGI VFTSGGENSH AVLKNAQRVG DVKDPFTIAE SVLKRASKEY FCTMYDITNY 300
  301 DTFEEFFAKK AARMGKFLKK GVPDVVAAAR SVLNDWNTGK IKYCT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.522879
Match: 2hjgA
Description: No description for 2hjgA was found.

Predicted Domain #3
Region A:
Residues: [418-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPPEVQEGQS VHISASIVHS EAREFDVENF ESMETEILEH CAVKTDDIME ITSTGPLEIR  60
   61 QPREEAEPAD KITASLVIDE KEKPAKGRKR KLDEEKEKVD PSLLLEENQS LNKGIKQMQK 120
  121 LKKKQNVRNE KKISKITDVL DSFSLGPSSS KAEKYDFDED YVIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.30103
Match: 1egaA
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.56635640666012 bayes_pls_golite062009
binding 1.9759530321894 bayes_pls_golite062009
nucleic acid binding 0.814319647681917 bayes_pls_golite062009
structural molecule activity 0.75789816397165 bayes_pls_golite062009
structural constituent of ribosome 0.710783021654704 bayes_pls_golite062009
protein binding 0.523813050066193 bayes_pls_golite062009
DNA binding 0.37695535646473 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle