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View Structure Prediction Details

Protein: CG16941-PA
Organism: Drosophila melanogaster
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG16941-PA.

Description E-value Query
Range
Subject
Range
gi|55244637, gi|... - gi|58376969|ref|XP_309321.2| ENSANGP00000008201 [Anopheles gambiae str. PEST], gi|55244637|gb|EAA051...
520.0 [0..22] [784..1]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLDAEANE EQFGNDQPKS MSGPIIGIIY PPPEVRNIVD KTASFVARNG PEFEARIRQN  60
   61 ELGNPKFNFL NGGDPYHAYY RHKVNEFREG NDAGITALAS MKQLAVTSAA QQRQQELLKQ 120
  121 VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 2dt6A
Description: No description for 2dt6A was found.

Predicted Domain #2
Region A:
Residues: [123-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQFVPKEPP PEFEFIADPP SISALDLDIV KLTAQFVARN GRQFLTNLMS REQRNFQFDF  60
   61 LRPQHSLFQY FTKLLEQYTK VLIPPKDLLG KLRSESAPGR SSMNQVLEQV KYRANWQRHQ 120
  121 EAQRRREEEK IERERVAYAQ IDWHDFVVVE TVDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 2dt7B
Description: No description for 2dt7B was found.

Predicted Domain #3
Region A:
Residues: [277-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPFESGNFPP PTNPDEVGAR VLMEERLMDE EGDTEMQIES DDEGDSQANN LLDSGLKLSQ  60
   61 MENRVGIQMK NVSSYGQPTG PKRDNTQVQD MDEASSDEDT PTTKLQPSVA PMLPPTHDKV 120
  121 VVKKYDPKAT QPKQAPMPTD EYLISPITGE KIPASKVSEH MRIGLLDPRW VEQRDKHTVE 180
  181 KINQDNVFAA GTAIEASLKQ LAERRTDIFG VGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [490-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EETVIGKKLG EEETKKDDRV TWDGHTSSVE AATRAARANI TLEEQIHQIH KVKGLLPDEE  60
   61 KEKIGPKPVG NKATLSAPPQ PSTKSQHSHS SQSQHHQGGG GGHHGHHNPH HHHPPHQQAP 120
  121 PHQSHHHHPP QQPQPVMQLM QLRPTMMQPP FGAGGGGYMN MQPGGIPQQI APAPPVDIME 180
  181 EEPPSKKIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [679-784]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDNLIPEAD FIATHKSPVT IQVLVPNSDK SEWKLNGQMI AVTMALSEPI ANLKTKLQDE  60
   61 TGMPPAKQKI FYEGMFFKDS NTMAFYNLVN GTTVHLQVKE RGGRKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1we7A
Description: Solution structure of Ubiquitin-like domain in SF3a120
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.786655943372 bayes_pls_golite062009
RNA binding 2.5865157751042 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
structural constituent of ribosome 1.967509006593 bayes_pls_golite062009
transcription regulator activity 1.96195140258726 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
DNA binding 1.68336605464756 bayes_pls_golite062009
structural molecule activity 1.52853261170163 bayes_pls_golite062009
tubulin binding 1.52077315590062 bayes_pls_golite062009
cytoskeletal protein binding 1.27084865380092 bayes_pls_golite062009
microtubule binding 1.2489441153237 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle