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View Structure Prediction Details

Protein: Abd-B-PB
Organism: Drosophila melanogaster
Length: 493 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Abd-B-PB.

Description E-value Query
Range
Subject
Range
gi|114620586 - gi|114620586|ref|XP_519780.2| PREDICTED: chromodomain helicase DNA binding protein 7 [Pan troglodyte...
179.0 [0..10] [493..74]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQHHLQQQQ QQQQQQEQQH LQEQQQHLQQ LHHHAHHHLP QPLHTTSHHH SAHPHLQQQQ  60
   61 QQQQHAVVAS SPSSVLQQQQ QQSTPTTHST PTHAVMYEDP PPVPLVAVQQ QHLPAPQQQQ 120
  121 QLQQQQQQQQ QQLATTPVAG AL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [143-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPAQTPTGPS AQQQQHLTSP HHQQLPQQQT PNSVASGASS NLQQQQQQQN AAVAPGQTQI  60
   61 VAPTTASVSP SSVSSQKEDI NMSIQLAPLH IPAIRAGPGF ETDTSAAVKR HTAHWAYNDE 120
  121 GFNQHYGSGY YDRKHMFAYP YPETQFPVGQ YWGPNYRPDQ TTSAAAAAAY MNEAERHVSA 180
  181 AARQSVEGTS TSSYEPPTYS SPGGLRGYPS ENYSSSGA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [361-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGLSVGAVG PCTPNPGLHE WTGQVSVRKK RKPYSKFQTL ELEKEFLFNA YVSKQKRWEL  60
   61 ARNLQLTERQ VKIWFQNRRM KNKKNSQRQA NQQNNNNNSS SNHNHAQATQ QHHSGHHLNL 120
  121 SLNMGHHAAK MHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1pufA
Description: Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.3573497204506 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
DNA binding 3.0205295442286 bayes_pls_golite062009
nucleic acid binding 2.77547609431902 bayes_pls_golite062009
transcription factor activity 2.57014522504183 bayes_pls_golite062009
transcription repressor activity 2.08714353704046 bayes_pls_golite062009
sequence-specific DNA binding 2.01558895662904 bayes_pls_golite062009
transcription activator activity 1.38536646126001 bayes_pls_golite062009
transcription factor binding 1.1887755957055 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.06075239560835 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
chromatin binding 0.807185147096719 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.57338514991304 bayes_pls_golite062009
transcription corepressor activity 0.336563012956291 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle