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View Structure Prediction Details

Protein: abd-A-PB
Organism: Drosophila melanogaster
Length: 590 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for abd-A-PB.

Description E-value Query
Range
Subject
Range
gi|109498320 - gi|109498320|ref|XP_001074557.1| PREDICTED: similar to dumpy CG33196-PB [Rattus norvegicus]
139.0 [0..3] [579..23]

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Predicted Domain #1
Region A:
Residues: [1-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKFVFDSML PKYPQFQPFI SSHHLTTTPP NSSSAAVAAA LAAAAASASA SVSASSSSNN  60
   61 NSSNTIAGSN TSNTNNSSSS PSSSSNNNSN LNLSGGSLSP SHLSQHLGQS PHSPVSSSSP 120
  121 FQQHHPQVQQ QHLNHQQQQH LHHQQQQHHH QYSSLSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [158-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALQLQQQQHH ISKLAAAAVA SHGHAHQQLL LTPPSAGNSQ AGDSSCSPSP SASGSSSLHR  60
   61 SLNDNSPGSA SASASASAAS SVAAAAAAAA AAASSSFAIP TSKMYPYVSN HPSSHGGLSG 120
  121 MAGFTGLEDK SCSRYT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [294-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTVMNSYQSM SVPASASAQF AQFYQHATAA ASAVSAASAG AIGVDSLGNA CTQPASGVMP  60
   61 GAGGAGGAGI ADLPRYPWMT LTDWMGSPFE 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [384-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVVCGDFNGP NGCPRRRGRQ TYTRFQTLEL EKEFHFNHYL TRRRRIEIAH ALCLTERQIK  60
   61 IWFQNRRMKL KKELRAVKEI NEQARRDREE QEKMKAQETM KSAQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 1b8iA
Description: Ultrabithorax (ubx) homeodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 3.00143272905695 bayes_pls_golite062009
nucleic acid binding 2.89825020286436 bayes_pls_golite062009
transcription factor activity 2.53664874743748 bayes_pls_golite062009
binding 1.68817361068715 bayes_pls_golite062009
sequence-specific DNA binding 0.46503550280898 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.24108783215685 bayes_pls_golite062009
transcription repressor activity 0.20862059645422 bayes_pls_golite062009
protein binding 0.111941607625758 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [489-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKQVQQQQQQ QQQQQQQQQQ QHQQQQQQPQ DHHSIIAHNP GHLHHSVVGQ NDLKLGLGMG  60
   61 VGVGVGGIGP GIGGGLGGNL GMMSALDKSN HDLLKAVSKV NS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle