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View Structure Prediction Details

Protein: sra-PA, FBpp0310844
Organism: Drosophila melanogaster
Length: 292 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sra-PA, FBpp0310844.

Description E-value Query
Range
Subject
Range
gi|74001209 - gi|74001209|ref|XP_849295.1| PREDICTED: similar to calcipressin 1 isoform a isoform 1 [Canis familia...
323.0 [0..90] [292..29]
gi|193787288, gi... - gi|33620725|ref|NP_004405.3| calcipressin 1 isoform a [Homo sapiens], gi|33149232|gb|AAP96743.1| cal...
319.0 [0..90] [290..32]
gi|114684002 - gi|114684002|ref|XP_001167915.1| PREDICTED: calcipressin 1 isoform 5 [Pan troglodytes]
318.0 [0..90] [290..32]
gi|109065409 - gi|109065409|ref|XP_001088613.1| PREDICTED: similar to calcipressin 1 isoform a isoform 2 [Macaca mu...
316.0 [0..90] [290..29]
gi|74145094, gi|... - gi|74145094|dbj|BAE27416.1| unnamed protein product [Mus musculus], gi|33149234|gb|AAP96744.1| calci...
314.0 [0..90] [290..29]
RCAN1_RAT - Calcipressin-1 OS=Rattus norvegicus GN=Rcan1 PE=2 SV=1
307.0 [0..106] [290..1]
gi|125777719, gi... - gi|54639453|gb|EAL28855.1| GA19337-PA [Drosophila pseudoobscura], gi|125777719|ref|XP_001359704.1| G...
307.0 [0..55] [292..1]
gi|50729949 - gi|50729949|ref|XP_416719.1| PREDICTED: similar to DSCR1-like protein [Gallus gallus]
306.0 [0..106] [290..44]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAAKSNNN ASADAPDPTT PDATGEADAA NAATPTTPRG NHNNNNSANG RSKNKLKSTQ  60
   61 NSSGGGSIDK LSPDQDIFIN AADGLPNQHP SLPKEGDVDS DTEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.229 a.24.10 Histidine-containing phosphotransfer domain, HPT domain

Predicted Domain #2
Region A:
Residues: [105-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVDADSFDDL PTSIIVTNIH SEVFANPELK HAMEELFRTF SESATFQWLR SFRRLRVNYD  60
   61 NAIAAANARI KLHQYEFNKK TVITCYFAQP VTPVSNKNLQ PPAPVKQFLI SPPASPPAGW 120
  121 EPREEGEPLV NHDLLAALAS LTPGESHELH PQSEDQPAII VHTAMLAETG PGLQVKAPIV 180
  181 QTKCPERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 1weyA
Description: Solution structure of RRM domain in calcipressin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.11118333721636 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
RNA binding 2.45916448091535 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.9432590957792 bayes_pls_golite062009
hydrolase activity 1.69824301409862 bayes_pls_golite062009
mRNA binding 1.62410365165765 bayes_pls_golite062009
transcription regulator activity 1.24650529385826 bayes_pls_golite062009
DNA binding 1.23082363146877 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 0.426324573266235 bayes_pls_golite062009
sequence-specific DNA binding 0.0605038543305221 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle