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View Structure Prediction Details

Protein: Sb-PA, FBpp0310459
Organism: Drosophila melanogaster
Length: 787 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sb-PA, FBpp0310459.

Description E-value Query
Range
Subject
Range
gi|549003, gi|15... - sp|Q05319|STUB_DROME Serine proteinase stubble (Stubble-stubbloid protein), gi|158512|gb|AAA28918.1...
483.0 [0..1] [787..1]

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Predicted Domain #1
Region A:
Residues: [1-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQPTLIRPR LRHRRSTPAA ATKMCPKRHW LVNNRAAGSR GSGGAAARSR RSLDQIVEVL  60
   61 VALIVVNCLA TAAAALITPP DSLESLGSLG IPSSSASSSE DDDDMSSGFY RIPHRLEGYP 120
  121 QLQQLQRGQN FKISPKPCSF GRVEGTCMFV WECIKSEGKH VGMCVDSFMF GSCCTHNYTD 180
  181 NIVLPQTAFS YTRPTKPLTL RPRPPAAPYK PMISGMTTIE RPHGAGTLVI RPSGPHHQGT 240
  241 LARPHPPPYQ SKPTTASDLH GSASHPSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [269-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSSSNP NSIWHTSTQQ QQQQQHQQNQ QNHWQMTTEP SFITKPRPTG WTKPGIVNLP  60
   61 MPARPSKPSK PTKKPIVYDR TPPPPPSVPP STSTSTTSTS LIWPAQTHPP QPHRPTRPQL 120
  121 SPGTSLAASS SSHWPSSTTS TTSSTTST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1ki0A
Description: Plasminogen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 2.17093251092775 bayes_pls_golite062009
binding 1.90408871052739 bayes_pls_golite062009
hydrolase activity 1.84706864202908 bayes_pls_golite062009
peptidase activity 1.80645788247419 bayes_pls_golite062009
signal transducer activity 1.66079544444023 bayes_pls_golite062009
molecular transducer activity 1.66079544444023 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.56029095187292 bayes_pls_golite062009
protein binding 1.52504676895038 bayes_pls_golite062009
endopeptidase activity 1.33798168430886 bayes_pls_golite062009
catalytic activity 0.280235123429996 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [417-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTTTTTTRRT TTPTTTTRRT TTNKPTRPYQ RPTTATSSSS TSTTSSKTPT TTRPISSSSS  60
   61 SSSGIVTSSQ RPTQPTHRTP VLATSGIETN EISDSSIPDA GALGHVKTIS AARSECGVPT 120
  121 LARPETRIVG GKSAAFGRWP WQVSVRRTSF FGFSSTHRCG GALINENWIA TAGHCVDDLL 180
  181 ISQIRIRVGE YDFSHVQEQL PYIERGVAKK VVHPKYSFLT YEYDLALVKL EQPLEFAPHV 240
  241 SPICLPETDS LLIGMNATVT GWGRLSEGGT LPSVLQEVSV PIVSNDNCKS MFMRAGRQEF 300
  301 IPDIFLCAGY ETGGQDSCQG DSGGPLQAKS QDGRFFLAGI ISWGIGCAEA NLPGVCTRIS 360
  361 KFTPWILEHV R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.154902
Match: 2f83A
Description: No description for 2f83A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle