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View Structure Prediction Details

Protein: stumps-PB
Organism: Drosophila melanogaster
Length: 1012 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for stumps-PB.

Description E-value Query
Range
Subject
Range
gi|7511846, gi|4... - pir||T13712 dof protein - fruit fly (Drosophila melanogaster), gi|4377453|emb|CAA09298.1| Dof prote...
1033.0 [0..1] [1012..1]

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Predicted Domain #1
Region A:
Residues: [1-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLKVENIEM ETFCCDNCGN VNNTSGSSAS GFLGSPGYNM DDILIITAKH SERAYLRATF  60
   61 LKNHFDKITK QRGRKPFNFL HIKIDDGPFS EEIAHKYQNT ALQIVILCPA LLALPHSFLM 120
  121 TQLSAIIRVE KVLAILLDVS EEKVKEMHKS ALPSYYKWRR CVVRDNDQVQ ISNILGIATD 180
  181 ILGRALCQRP PCQDSSGGGG GGLSRSFSSC TEGFTVLPKK VKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [224-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQNKVVALLA EPLEKNDTLK LQVEKSGELI ELRNFKCRNP YTLQFNIPEA CMEISTMIEI  60
   61 RIEKNNKSLG ARPIKCESRL RELEQLLRIE DSPIEFMCHA LGIGPVERDA LDQHLLQCFQ 120
  121 RNMPPNFHLL SGPSERQPHF FTRLESSPEE YPTLLHFAAR WGLNRLCIQL MECPGGDTAC 180
  181 GVRNCAGRTP AELAEQEGHH KLAQNIVSFA EFHELTTMYH YFKGVTPPGE SCPKPSANVV 240
  241 IEAHPVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1k1aA
Description: bcl-3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.96927469603571 bayes_pls_golite062009
protein binding 1.64872738860757 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [471-648]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGKTNKPPKE LPTAEYMEMS SGSERENTPE VRTKTETLAI SNLNYISVET EDENLQASVA  60
   61 EKKVESEKKL PEAGNQPGPE KTTNELRINE PPYYQSKEQN QQPKELKNQS KSLDEVDAAP 120
  121 LYQTDKFSQE CSQLLENQLG NDYVLQPSNV PVAQDDGNYL FQPSNRPVEE PLRLNRCT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1k3zD
Description: Transcription factor inhibitor I-kappa-B-beta, IKBB
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [649-884]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRQPGYGTLK RSASDASAAS HTRSNADDEL AEIMHDFKNN VLSIRDVEVL VERWKHRNDV  60
   61 QQSFREKQDQ IDQLRREYER IQEQVKSHLK RETPFERIKK FFLRSKTPGG NDSLLDETKS 120
  121 SIATSCSFKS AGGVSSSAGA GRPISSLSLQ SVSSSSSSSG RLSTGSNCSG ASLGDSGTHS 180
  181 DHEDRRFPHC RMMDNYMVPP TPRPVFTPSS TPGDERHQIV FPSPMSSCQR LNTPTS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [885-1012]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTGSEHYQMF PSNIPVYGSQ PLVGSQSSNY LNTIMEAKEQ AETQHYQNQN GVTLQPIKLN  60
   61 ERSNIIYGKL TKSSSASGCS SFKPKQIPVP CPQVGSIEVQ AEVYQNVGDV APEKDSKAEE 120
  121 ETPNYMNC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle