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View Structure Prediction Details

Protein: rin-PE, FBpp0312...
Organism: Drosophila melanogaster
Length: 690 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rin-PE, FBpp0312....

Description E-value Query
Range
Subject
Range
gi|7739653 - gi|7739653|gb|AAF68949.1|AF231031_1 rasputin [Drosophila melanogaster]
244.0 [0..1] [675..1]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMDATQSQQ PSPQSVGREF VRQYYTLLNK APNHLHRFYN HNSSYIHGES KLVVGQREIH  60
   61 NRIQQLNFND CHAKISQVDA QATLGNGVVV QVTGELSNDG QPMRRFTQTF VLAAQSPKKY 120
  121 YVHNDIFRYQ DLYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1a2kA
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.88422211140837 bayes_pls_golite062009
protein binding 1.34243535208605 bayes_pls_golite062009
protein transporter activity 0.960383711156379 bayes_pls_golite062009
transporter activity 0.55283159394909 bayes_pls_golite062009
RNA binding 0.541310012083998 bayes_pls_golite062009
Ran GTPase binding 0.437541267934309 bayes_pls_golite062009
small GTPase binding 0.16703540602196 bayes_pls_golite062009
GTPase binding 0.15019810567677 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEQDGESRS ENDEEHDVQV VGGTVDQAVQ VAGDVVAQQP QQQQAPPQPQ AQVVVPQQVA  60
   61 PVAAGGAAPQ QIFYPLPAGA AA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [217-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRPVAVLPPA PQAAAVPLPA QFTVPPPQPI QNGVVSHEEL QQQQVLVPPS VSPLVQQQQP  60
   61 TGTPVLPIVP VPSAGFQQSP LVAPQLIQQQ QQQQPAQLPP QQQQQQQPIQ QQQPLQQQQQ 120
  121 PLAEPEEVEV APRQQKPPTP VEDFKTIHEQ QQQEKYEAAK QQQNEPKTYA NLFKSTSSSP 180
  181 SGFVNAALQQ QQQLQQQQQQ QQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [419-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISSNTYNSS SATSGGGNGS QVSYSTTASS YNNSNGNSRL DNGGPLPQRN NSIRNNKGDF  60
   61 EQRRSSNTQQ FGDNQQLFLG NIPHHASEDD LREIFSRFGN VLELRILSKA GNKVPPGMRS 120
  121 PLNYGFITYD DPEAVQKCLA NCPLYFPENS PDGQKLNVEE KKPRVRNDMV PRQQIGGNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.221849
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.00411894202318 bayes_pls_golite062009
RNA binding 2.99069397581023 bayes_pls_golite062009
nucleic acid binding 2.31150433509655 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA binding 0.505477067109476 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [598-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNNNMGRLGG NNGPQSRPMG NNNGSGGGMM RNNAGGNNLR QGGGGGNGAP RLGGGGGFGQ  60
   61 RQDNRTGGGN NQSNGPLRGA GNGQSGGGNY GRR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle