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View Structure Prediction Details

Protein: CG9799-PA
Organism: Drosophila melanogaster
Length: 922 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9799-PA.

Description E-value Query
Range
Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
748.0 [0..2] [748..746]

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Predicted Domain #1
Region A:
Residues: [1-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHLRSEDKP QSEERKSVFK ESSCIFRRNR ALGYVSNQVP AVTRYVQRRR DTLLITCIGR  60
   61 SFQVYTANHF RLLHVSGLHP DEITALATDR LHTYTASNKC IYAWRAGKHI RHVYRGHQKD 120
  121 VHLLLPFGSS LIAIDRQNVL KVWNISTEDV YLEVPFRSEE FQITAVTHPP TYINKIVLGS 180
  181 QQGQLKILNI KKNSVVCTLS HHDSRITCIE PSPALDVVAV GHGDGTIILL NLKFDEVLMS 240
  241 FQQDWGQVTN LSFRTDGPPI LVSACSNGYM AFWNLEERKL AGQLQAHEES VTTAICLPSE 300
  301 PVVFTTSPDN SMRMFVFDMP DGGARQLRIR EGHTKPPFCI RYHGSSGVSI LSSGEDSTMR 360
  361 VFSTISESLN KSMGRATYNP KATKKKNRFE HDKFGMPPIL EFTSDTAREK EWDNIAAIHA 420
  421 GVIQTTTWSF GKNRMGEHRL VPKQFQNSNR TNFQNETTCI VLTHCGNFVI IGYSSGDIER 480
  481 FNIQSGLHRA TYGSPAHKMA VRGLASDNLN QTVISGCSEG LLKFWSFKGK VDKPLATLRL 540
  541 ADGIALIRQH RESSMLAIGL ETFKIFVVDM HTRVIVRKFV GHTAKLNDLT FSPDSRWLIT 600
  601 AAMDSTIKVW DIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.221849
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 2.22722319261713 bayes_pls_golite062009
cytoskeletal protein binding 1.5283366007575 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
nucleic acid binding 1.20712373307552 bayes_pls_golite062009
structural molecule activity 1.20572493724069 bayes_pls_golite062009
protein binding 1.11897341394404 bayes_pls_golite062009
actin binding 0.794986868016276 bayes_pls_golite062009
DNA binding 0.711274653406079 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
tubulin binding 0.0577116761374565 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [614-748]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSYMVDHFRV EAPCVSLSMS PNGDFLATAH VGLLGIYLWA NKTLFNQISL RSIDPLEPAP  60
   61 YVGLPTNVCD AMELEDGMKE LEIDEEDESK LGELVDTKYE TPTQLSEELI TLSGLAASRW 120
  121 QNLLDLELIK QRNKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.39794
Match: 1gxrA
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [749-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAPPKAPKQA PFFLPTVSGL ELRFDVENGQ KEEDESRIRK ASTLNNLTAF GQLLEETADS  60
   61 LDFASAVAHL TQLGPSMVDF EIKSLHPEAG GTLLAMLQFL KLVKFMFGTN LNFELAQSYL 120
  121 SVFLRSHGLG LTEFPDLVKE LRTVSQVQQE AWQRVEEKLI YGTGVVAALR NFAH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle