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View Structure Prediction Details

Protein: glo-PA, glo-PB
Organism: Drosophila melanogaster
Length: 586 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for glo-PA, glo-PB.

Description E-value Query
Range
Subject
Range
gi|73976775 - gi|73976775|ref|XP_539581.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
229.0 [0..1] [454..125]

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Predicted Domain #1
Region A:
Residues: [1-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNADVQFNY GQQGNGDNFN DDSNQQQDED DQYNEDGGGK IENVGESPKF VRLRGLPWSA  60
   61 THKEILDFLE NVNVTNGSAG IHLVTSRVDG KNTGEAYVEV ASQEDVEEAR KLNKASMGHR 120
  121 YIEVFTATPK EAKEAMRKIS GHGTAFVVKL RGLPYAVTEQ QIEEFFSGLD IKTDREGILF 180
  181 VMDRRGRATG EAFVQFESQD DTEQALGRNR EKIGHRYIEI FRSSIAEMKR ATGAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1up1A
Description: UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [236-449]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGVGGRPGPY DIRDRGANRG GNDFGGGRND WGNNGNFGVG ANNMLGFNNL PSLMNSGNFG  60
   61 NNQGGNNGNF GNNSGPSNFG NFGGGNNGGN SGNFGNDSGN SGNFGNFGNN GGGNFGGNNN 120
  121 GGGGFNSGNN FNSPGGVNNF GNNGGSNFGG NGGGGFNNGG NFVSSSGVGN FGPIGGGRNN 180
  181 NNGNFGNSGF GNFGGNNNVG SNFGGGNNGG GGGF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [450-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNGSNFGGGN SMGGGGNFGP IGGGRGNDIE YYTIHMRGLP YTSFENDVFK FFEPIRPANV  60
   61 RINYNKKGLH SGTADAYFDT YEDSQVAMKR HREQMGSRYI ELFYDGKTRG LNGGEHGGGN 120
  121 GGGGMGNNGG GNFSRRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2hgnA
Description: No description for 2hgnA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle