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View Structure Prediction Details

Protein: PGRP-LB-PB, PGRP...
Organism: Drosophila melanogaster
Length: 215 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGRP-LB-PB, PGRP....

Description E-value Query
Range
Subject
Range
PGRP-LB-PC - The gene Peptidoglycan recognition protein LB is referred to in FlyBase by the symbol Dmel\PGRP-LB (...
gi|220959668, gi... - gi|220959668|gb|ACL92377.1| PGRP-LB-PA [synthetic construct], gi|220951128|gb|ACL88107.1| PGRP-LB-PA...
233.0 [0..1] [215..18]
gi|60688419, gi|... - gi|71896011|ref|NP_001025626.1| pglyrp1 protein [Xenopus (Silurana) tropicalis], gi|60688419|gb|AAH9...
204.0 [0..4] [177..10]
gi|62643834, gi|... - gi|62643834|ref|XP_574982.1| PREDICTED: similar to peptidoglycan recognition protein 3 [Rattus norve...
195.0 [0..11] [177..175]
gi|44921643, gi|... - gi|46402249|ref|NP_997130.1| peptidoglycan recognition protein 3 [Mus musculus], gi|44921643|gb|AAS4...
194.0 [0..11] [177..183]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQANLGDGV ATARLLSRSD WGARLPKSVE HFQGPAPYVI IHHSYMPAVC YSTPDCMKSM  60
   61 RDMQDFHQLE RGWNDIGYSF GIGGDGMIYT GRGFNVIGAH APKYNDKSVG IVLIGDWRTE 120
  121 LPPKQMLDAA KNLIAFGVFK GYIDPAYKLL GHRQVRDTEC PGGRLFAEIS SWPHFTHIND 180
  181 TEGVSSTTAP VVPHVHPQAA APQKPHQSPP AAPKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.69897
Match: 1ohtA
Description: Peptidoglycan recognition protein-lb (Cg14704)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidoglycan binding 9.32313496679335 bayes_pls_golite062009
peptidoglycan receptor activity 6.51660037886232 bayes_pls_golite062009
pattern recognition receptor activity 6.45255811818702 bayes_pls_golite062009
N-acetylmuramoyl-L-alanine amidase activity 5.29207604418857 bayes_pls_golite062009
pattern binding 4.06455798515101 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.20235326428146 bayes_pls_golite062009
receptor activity 2.69681086194598 bayes_pls_golite062009
signal transducer activity 2.24692953747972 bayes_pls_golite062009
molecular transducer activity 2.24692953747972 bayes_pls_golite062009
binding 1.78736719382897 bayes_pls_golite062009
muramyl dipeptide binding 1.16811676642278 bayes_pls_golite062009
hydrolase activity 1.14017500144843 bayes_pls_golite062009
0.808368163500401 bayes_pls_golite062009
catalytic activity 0.628556091191359 bayes_pls_golite062009
0.60706691535931 bayes_pls_golite062009
protein binding 0.175384917086218 bayes_pls_golite062009

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