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View Structure Prediction Details

Protein: tws-PA, FBpp0311...
Organism: Drosophila melanogaster
Length: 499 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tws-PA, FBpp0311....

Description E-value Query
Range
Subject
Range
gi|48893630, gi|... - gi|71673807|ref|ZP_00671555.1| TPR repeat:G-protein beta WD-40 repeat:YD repeat [Trichodesmium eryth...
483.0 [0..4] [496..1003]

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Predicted Domain #1
Region A:
Residues: [1-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRWGRQSPV LEPPDPQMQT TPPPPTLPPR TFMRQSSITK IGNMLNTAIN INGAKKPASN  60
   61 GEASWCFSQI KGALDDDVTD ADIISCVEFN HDGELLATGD KGGRVVIFQR DPASKAANPR 120
  121 RGEYNVYSTF QSHEPEFDYL KSLEIEEKIN KIRWLQQKNP VHFLLSTNDK TVKLWKVSER 180
  181 DKSFGGYNTK EENGLIRDPQ NVTALRVPSV KQIPLLVEAS PRRTFANAHT YHINSISVNS 240
  241 DQETFLSADD LRINLWHLEV VNQSYNIVDI KPTNMEELTE VITAAEFHPT ECNVFVYSSS 300
  301 KGTIRLCDMR SAALCDRHSK QFEEPENPTN RSFFSEIISS ISDVKLSNSG RYMISRDYLS 360
  361 IKVWDLHMET KPIETYPVHE YLRAKLCSLY ENDCIFDKFE CCWNGKDSSI MTGSYNNFFR 420
  421 VFDRNSKKDV TLEASRDIIK PKTVLKPRKV CTGGKRKKDE ISVDCLDFNK KILHTAWHPE 480
  481 ENIIAVAATN NLFIFQDKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.39794
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
actin binding 2.27900251096697 bayes_pls_golite062009
hydrolase activity 1.72636554646684 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
nucleic acid binding 0.693814013902061 bayes_pls_golite062009
transcription regulator activity 0.579815310385678 bayes_pls_golite062009
actin filament binding 0.554537899540618 bayes_pls_golite062009
kinase activity 0.498626428956965 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.496422970081867 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.326899344050856 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
protein kinase activity 0.245792286293244 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
DNA binding 0.0736878329528894 bayes_pls_golite062009
0.0248988265652406 bayes_pls_golite062009

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