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View Structure Prediction Details

Protein: gi|23170716, gi|...
Organism: Drosophila melanogaster
Length: 404 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23170716, gi|....

Description E-value Query
Range
Subject
Range
Dhod-PA, Dhod-PD - The gene Dihydroorotate dehydrogenase is referred to in FlyBase by the symbol Dmel\Dhod (CG9741, FBg...
gi|220950570, gi... - gi|220959410|gb|ACL92248.1| Dhod-PA [synthetic construct], gi|220950570|gb|ACL87828.1| Dhod-PA [synt...
330.0 [0..1] [404..1]

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Predicted Domain #1
Region A:
Residues: [1-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQDHLKNAK NATRRGRLRS LGIVTVGGAA LVAGITAYKN QDQLFRTFVM PAVRLLPAEA  60
   61 SHQLAVLACK YRLCPVSQYH DDQNLHTSFF GRMLSNPIGI AAGFDKNAEA VDGLQDLGFG 120
  121 FIEVGTVTPA AQEGNPKPRV FRLTEDKAII NRYGFNSDGH QAVLQRLRLL RKKENFNGVV 180
  181 GVNLGRNKTT MSPIADYVQG VRVFGPVADY LVINVSSPNT KGLRDMQSKE KLRELLEQVN 240
  241 DTKSSLDKNK NVPILLKLSP DLSLDDMKDI VWVIKRKKSR VDGLIVSNTT VSRENIEKNK 300
  301 LAEETGGLSG PPLKARSTEM IAQMYQLTDG KIPIIGVGGV ASGYDAYEKI EAGASYVQIY 360
  361 TALVYEGPAL VEDIKAELSA LITRLGHTNV ADVVGTNSKF YLPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.69897
Match: 1uumA
Description: Rat dihydroorotate dehydrogenase (DHOD)in complex with atovaquone
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 2.7385769437489 bayes_pls_golite062009
dihydroorotate dehydrogenase activity 2.73800716363956 bayes_pls_golite062009
dihydroorotate oxidase activity 2.35584458985229 bayes_pls_golite062009
catalytic activity 1.94749091175302 bayes_pls_golite062009
dihydropyrimidine dehydrogenase (NADP+) activity 1.76080169529176 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 0.962937319088834 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.876786102965635 bayes_pls_golite062009
nucleic acid binding 0.126127705865716 bayes_pls_golite062009
binding 0.100344139383616 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle